Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.54 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561353 | 0.90 | ALDH1A1 (0.54) | ALDH1A1HSD17B10POLBCYP26A1KMT2A | |
| SCHEMBL3564056 | 0.90 | ALDH1A1 (0.54) | ALDH1A1HSD17B10POLBCYP26A1KMT2A | |
| SCHEMBL3557383 | 0.85 | MAPT (0.67) | ALDH1A1HSD17B10POLBCYP26A1HSD17B13 | |
| SCHEMBL3554420 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HSD17B10POLBCYP26A1HSD17B13 | |
| SCHEMBL3557287 | 0.84 | SLC16A3 (0.64) | ALDH1A1HSD17B10KMT2AGAAHPGD | |
| SCHEMBL3555496 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HSD17B10POLBKMT2AGAA | |
| SCHEMBL3556553 | 0.82 | ALDH1A1 (0.73) | ALDH1A1HSD17B13KMT2AGAAHPGD | |
| SCHEMBL3552657 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HSD17B10KMT2APTPN5HPGD | |
| SCHEMBL3553525 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10KMT2AGAAHPGD | |
| SCHEMBL3564236 | 0.81 | SLC16A3 (0.59) | ALDH1A1CYP26A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | ALDH1A1 61/4885HSD17B10 236/4885POLB 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.