Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 8/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554726 | 0.94 | SLC16A3 (0.64) | SLC16A3AKR1C3ABCB1KEAP1NFE2L2 | |
| SCHEMBL3561105 | 0.91 | SLC16A3 (0.76) | SLC16A3AKR1C3ABCB1KEAP1NFE2L2 | |
| SCHEMBL3561861 | 0.91 | SLC16A3 (0.70) | SLC16A3AKR1C3ABCB1KEAP1NFE2L2 | |
| SCHEMBL3552744 | 0.88 | SLC16A3 (0.85) | SLC16A3AKR1C3RAB9AKDM4ETSHR | |
| SCHEMBL3555853 | 0.87 | KEAP1 (0.56) | SLC16A3AKR1C3KEAP1NFE2L2 | |
| SCHEMBL3561649 | 0.87 | SLC16A3 (0.73) | SLC16A3KEAP1NFE2L2RAB9AACLY | |
| SCHEMBL3556199 | 0.86 | SLC16A3 (0.74) | SLC16A3AKR1C3RAB9AKDM4ETSHR | |
| SCHEMBL3558727 | 0.85 | SLC16A3 (0.76) | SLC16A3ABCB1KDM4ETSHR | |
| SCHEMBL3562818 | 0.85 | AKR1C3 (0.66) | SLC16A3AKR1C3HDAC3HDAC1 | |
| SCHEMBL3560916 | 0.85 | SLC16A3 (0.62) | SLC16A3AKR1C3KEAP1NFE2L2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | SLC16A3 425/4885AKR1C3 23/4885ABCB1 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.