⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740414 | 0.65 | — | — | |
| SCHEMBL643818 | 0.63 | — | — | |
| SCHEMBL21402003 | 0.63 | — | — | |
| SCHEMBL29246044 | 0.63 | — | — | |
| SCHEMBL15658915 | 0.61 | CA1 (0.31) | — | |
| SCHEMBL31747873 | 0.59 | — | — | |
| SCHEMBL28326572 | 0.59 | — | — | |
| SCHEMBL9018641 | 0.58 | — | — | |
| SCHEMBL15364712 | 0.56 | — | — | |
| SCHEMBL15618412 | 0.55 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |
| EP-2780342-B1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2016-06-01 | — | — | EP | disclosed |
| CN-102898522-B | Tetrahydropyridinopyran-monoclonal antibody CD14 conjugate with anti-tumor activity and preparation method and use thereof | UNIV SHANGHAI | 2014-12-31 | — | — | CN | disclosed |
| CN-102898522-A | Tetrahydropyridinopyran-monoclonal antibody CD14 conjugate with anti-tumor activity and preparation method and use thereof | UNIV SHANGHAI | 2013-01-30 | — | — | CN | disclosed |
| US-7696354-B2 | Cephem compounds having broad antibacterial spectrum | SHIONOGI & CO., LTD. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20090131655-A1 | Cephem Compounds Having Broad Antibacterial Spectrum | SHIONOGI & CO., LTD. | 2009-05-21 | — | — | US | disclosed |
| US-7384928-B2 | Broad spectrum cephem compounds | SHIONOGI & CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20050153950-A1 | Broad -spectrum cephem compounds | SHIONOGI & CO., LTD. (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1489084-A1 | BROAD-SPECTRUM CEPHEM COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 2004-12-22 | — | — | EP | disclosed |