Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 7/20 | 0.63 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | WDR5 | P61964 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561921 | 0.95 | SLC16A3 (0.70) | SLC16A3KAT6AMETAP2WDR5MCL1 | |
| SCHEMBL3565536 | 0.90 | SLC16A3 (0.68) | SLC16A3KAT6AMETAP2MCL1MEN1 | |
| SCHEMBL3564970 | 0.89 | SLC16A3 (0.59) | SLC16A3METAP2WDR5MCL1BCL2A1 | |
| SCHEMBL3562556 | 0.89 | SLC16A3 (0.67) | SLC16A3MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3563748 | 0.88 | SLC16A3 (0.68) | SLC16A3KAT6AMETAP2MCL1MEN1 | |
| SCHEMBL3554625 | 0.87 | SLC16A3 (0.69) | SLC16A3KAT6AMETAP2MEN1KMT2A | |
| SCHEMBL3557013 | 0.87 | SLC16A3 (0.74) | SLC16A3KAT6AMETAP2MEN1KMT2A | |
| SCHEMBL3555460 | 0.86 | SLC16A3 (0.74) | SLC16A3KAT6AMETAP2MCL1 | |
| SCHEMBL3558496 | 0.86 | SLC16A3 (0.70) | SLC16A3METAP2 | |
| SCHEMBL3562391 | 0.86 | WDR5 (0.58) | METAP2WDR5MCL1BCL2A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | SLC16A3 425/4885KAT6A 4632/4885METAP2 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.