Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | XBP1 | P17861 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20700503 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL20700102 | 0.81 | MAPT (0.53) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL7396662 | 0.80 | L3MBTL1 (0.63) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL20921292 | 0.80 | L3MBTL1 (0.63) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL20700525 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL3456382 | 0.78 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL14452010 | 0.78 | TAAR1 (0.60) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL19258004 | 0.78 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL30782878 | 0.78 | TAAR1 (0.60) | ALDH1A1L3MBTL1GAAKMT2ALMNA | |
| SCHEMBL20700121 | 0.78 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1GAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671072-B2 | Aminopyrazole derivatives as GSK-3 inhibitors | PFIZER INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20070276010-A1 | Aminopyrazole Derivatives as Gsk-3 Inhibitors | BENBOW JOHN W | 2007-11-29 | — | — | US | disclosed |
| WO-2007123941-A2 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276010-A1 | Aminopyrazole Derivatives as Gsk-3 Inhibitors | GSK3B, GSK3A, GSKIP | ALDH1A1 1036/4885L3MBTL1 1447/4885GAA 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.