Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.62 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.62 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KDM5C | P41229 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL35434 | 0.87 | — | — | |
| Glycine SCHEMBL1947837 | 0.85 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2KDM4EKDM5C | |
| Glycine SCHEMBL5229648 | 0.84 | — | — | |
| Glycine SCHEMBL474856 | 0.79 | — | — | |
| Glycine SCHEMBL28317820 | 0.79 | — | — | |
| Glycine SCHEMBL3384608 | 0.79 | — | — | |
| Methylamine SCHEMBL2821987 | 0.79 | — | — | |
| Glycine SCHEMBL246859 | 0.79 | GLRA1 (0.83) | GLRA1SLC6A9OR51E2KDM4EEGLN1 | |
| Glycine SCHEMBL3640989 | 0.79 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2KDM4EEGLN1 | |
| Glycine SCHEMBL391786 | 0.79 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2KDM4EEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7740696-B2 | Water-soluble azo compound, ink composition, and colored article | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20090117341-A1 | Water-Soluble Azo Compound, Ink Composition, and Colored Article | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-05-07 | — | — | US | disclosed |