⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30935741 | 0.83 | — | — | |
| SCHEMBL18048378 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL3501857 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL19445479 | 0.79 | — | — | |
| SCHEMBL1976528 | 0.79 | — | — | |
| SCHEMBL27457178 | 0.75 | MVD (0.33) | — | |
| SCHEMBL28992260 | 0.73 | — | — | |
| SCHEMBL21702799 | 0.73 | CTSA (0.31) | — | |
| SCHEMBL27689139 | 0.72 | — | — | |
| SCHEMBL22652 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201942-A | Modified short interfering nucleic acid (siNA) molecules and uses thereof | 阿利戈斯治疗公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116568666-A | Method for purifying ethylene cyanohydrin | 赢创运营有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-110325543-B | Cyclic dinucleotides as STING (stimulator of interferon genes) agonists | 武田药品工业株式会社 | 2023-03-31 | — | — | CN | disclosed |
| CN-110382515-B | Modified cyclic dinucleotide compounds | 勃林格殷格翰国际有限公司 | 2023-03-03 | — | — | CN | disclosed |
| US-10125217-B2 | Method for producing polyether carbonate polyols | COVESTRO DEUTSCHLAND AG (DE) | 2018-11-13 | — | — | US | disclosed |
| US-10040901-B2 | Method for producing polyether carbonate polyols | COVESTRO DEUTSCHLAND AG (DE) | 2018-08-07 | — | — | US | disclosed |
| US-20170137569-A1 | Method for Producing Polyether Carbonate Polyols | COVESTRO DEUTSCHLAND AG (DE) | 2017-05-18 | — | — | US | disclosed |
| US-RE46171-E1 | Functional biopolymer modification reagents and uses thereof | SOLULINK, INCORPORATED (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160264727-A1 | METHOD FOR PRODUCING POLYETHER CARBONATE POLYOLS | COVESTRO DEUTSCHLAND AG (DE) | 2016-09-15 | — | — | US | disclosed |
| US-7732628-B2 | Such as 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]benzaldehyde, 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]acetophenone; for incorporation into oligonucleotides during immobilization and conjugation of biopolymers in solid phase synthesis | SOLULINK INCORPORATED (US) | 2010-06-08 | — | — | US | disclosed |
| WO-2006093526-A2 | OLIGONUCLEOTIDES COMPRISING A MODIFIED OR NON-NATURAL NUCLEOBASE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| US-7102024-B1 | Functional biopolymer modification reagents and uses thereof | AUDAX PRIVATE DEBT LLC, AS AGENT | 2006-09-05 | — | — | US | disclosed |
| US-20050203289-A1 | Functional biopolymer modification reagents and uses thereof | AUDAX PRIVATE DEBT LLC, AS AGENT | 2005-09-15 | — | — | US | disclosed |
| WO-2002010431-A2 | FUNCTIONAL BIOPOLYMER MODIFICATION REAGENTS AND USES THEREOF | SCHWARTZ DAVID A (US) | 2002-02-07 | — | — | WO | disclosed |
| EP-1102787-A1 | 2'-O-AMINOETHYLOXYETHYL-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000008044-A1 | 2'-O-AMINOETHYLOXYETHYL-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
| US-5932718-A | CONTACTING NUCLEOTIDE OR OLIGONUCLEOTIDE HAVING 5' H-PHOSPHONATE DERIVATIVE WITH 5'-O-TRITYL-3'-AMINO-2'-DEOXYRIBONUCLEOSIDE IN PRESENCE OF OXIDIZING AGENT PRODUCING PROTECTED INTERNUCLEOSIDE LINKAGE | NORTHWESTERN UNIVERSITY (US) | 1999-08-03 | — | — | US | disclosed |
| US-5648480-A | Process for making oligonucleotides having modified internucleoside linkages | NORTHWESTERN UNIVERSITY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5646260-A | PHOSPHORYLATED OLIGONUCLEOTIDES | LETSINGER ROBERT L (US) | 1997-07-08 | — | — | US | disclosed |
| US-5476925-A | Antisense agents | NORTHWESTERN UNIVERSITY (US) | 1995-12-19 | — | — | US | disclosed |