SCHEMBL3501857

SCHEMBL3501857

CC(C)N(C(C)C)P(=O)(OCCC#N)N(C(C)C)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
NLRP3 Q96P20 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18048378 0.85 TSHR (0.30) TSHRNLRP3
SCHEMBL19445479 0.81
SCHEMBL1976528 0.81
SCHEMBL3565320 0.81
SCHEMBL25192455 0.74
SCHEMBL30935741 0.72
SCHEMBL14189792 0.71 CTSA (0.33) TSHR
SCHEMBL20581718 0.70
SCHEMBL20581719 0.70
SCHEMBL28992261 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5202090-A None JP disclosed
US-20260132165-A1 MODIFIED NUCLEOSIDE ANALOGUE AND USE THEREOF, AND NUCLEOSIDE ANALOGUE-CONTAINING DOUBLE-STRANDED OLIGONUCLEOTIDE AND USE THEREOF RIGERNA THERAPEUTICS (BEIJING) CO., LTD. (CN) 2026-05-14 US disclosed
EP-4707392-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE, CONJUGATE THEREOF, AND USE THEREOF Rigerna Therapeutics (Beijing) Co., Ltd. (CN) 2026-03-11 EP disclosed
US-20250257356-A1 COMPOSITION AND METHOD FOR INHIBITING EXPRESSION OF PROTEIN LPA(APO(A)) SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD. (CN) 2025-08-14 US disclosed
EP-4585603-A1 GALNAC COMPOUND COMPRISING RIBOSE RING OR DERIVATIVE STRUCTURE THEREOF, AND OLIGONUCLEOTIDE CONJUGATE THEREOF Hangzhou Tianlong Pharmaceutical Co., Ltd. (CN) 2025-07-16 EP disclosed
EP-4471144-A1 COMPOSITION AND METHOD FOR INHIBITING EXPRESSION OF PROTEIN LPA(APO(A)) Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2024-12-04 EP disclosed
WO-2024235124-A1 MODIFIED NUCLEOSIDE ANALOGUE AND USE THEREOF, AND NUCLEOSIDE ANALOGUE-CONTAINING DOUBLE-STRANDED OLIGONUCLEOTIDE AND USE THEREOF 北京炫景瑞医药科技有限公司 2024-11-21 WO disclosed
CN-118401539-A Functionalized N-acetylgalactosamine analogues 兆维生物科技公司 2024-07-26 CN disclosed
CN-118317970-A Synthesis of 2' acetyl-ester protected nucleosides 兆维生物科技公司 2024-07-09 CN disclosed
CN-117866030-A Cyclic dinucleotide compounds for the treatment of cancer 卫材 R&D 管理有限公司 2024-04-12 CN disclosed
US-20130137755-A1 SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI SEGEV LABORATORIES LIMITED (IL) 2013-05-30 US disclosed
US-20110065909-A1 SYNTHESIS OF OLIGONUCLEOTIDES GIRINDUS AG (DE) 2011-03-17 US disclosed
US-7678542-B2 Charge tags and the separation of nucleic acid molecules THIRD WAVE TECHNOLOGIES, INC. (US) 2010-03-16 US disclosed
US-20090078574-A1 CHARGE TAGS AND THE SEPARATION OF NUCLEIC ACID MOLECULES THIRD WAVE TECHNOLOGIES, INC. (US) 2009-03-26 US disclosed
US-20080051323-A1 Chloroquine drug compositions and methods for their synthesis KOSAK KENNETH M 2008-02-28 US disclosed
WO-2007050789-A2 GLYCOSYL-OLIGONUCLEOTIDE CONJUGATES AND METHODS NËDKEN CORPORATION (US) 2007-05-03 WO disclosed
EP-1156054-B1 DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2004-04-14 EP disclosed
US-6495533-B1 TUMOR NECROSIS FACTOR INHIBITORS; RHEUMATOID ARTHRITIS, ULCERATIVE COLITIS, CROHN'S DISEASE, HEPATITIS, SEPSIS, HEMORRHAGIC SHOCK, MULTIPLE SCLEROSIS, CEREBRAL INFARCTION, DIABETES, INTERSTITIAL PNEUMONIA, PAIN, HIV ONO PHARMACEUTICAL CO., LTD. (JP) 2002-12-17 US disclosed
EP-1156054-A1 DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2001-11-21 EP disclosed
JP-H05202090-A NOVEL ANTISENSE OLIGONUCLEOTIDES HAVING PHOSPHORAMIDATE-CROSSLINKAGE AMONG NUCLEOTIDES THEREOF THROUGHOUT THE SAME BAYER AG 1993-08-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065909-A1 SYNTHESIS OF OLIGONUCLEOTIDES RNGTT, CPSF1, CPSF6 TSHR 1119/4885NLRP3 4621/4885
US-20260132165-A1 MODIFIED NUCLEOSIDE ANALOGUE AND USE THEREOF, AND NUCLEOSIDE ANALOGUE-CONTAINING DOUBLE-STRANDED OLIGONUCLEOTIDE AND USE THEREOF NSUN2, TK1, SLC28A2 TSHR 1898/4885NLRP3 4556/4885
US-20250257356-A1 COMPOSITION AND METHOD FOR INHIBITING EXPRESSION OF PROTEIN LPA(APO(A)) APOB, LPAR2, LPAR1 TSHR 4091/4885NLRP3 4137/4885
US-20130137755-A1 SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI NFATC1, KPNA2, KPNA6 TSHR 1529/4885NLRP3 4659/4885
US-20080051323-A1 Chloroquine drug compositions and methods for their synthesis CHMP4B, CTSA, CLTA TSHR 4791/4885NLRP3 833/4885
US-20090078574-A1 CHARGE TAGS AND THE SEPARATION OF NUCLEIC ACID MOLECULES NSUN2, NSUN3, NCL TSHR 2375/4885NLRP3 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.