⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048378 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL3501857 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL19445479 | 0.79 | — | — | |
| SCHEMBL3565320 | 0.79 | — | — | |
| SCHEMBL20581719 | 0.75 | — | — | |
| SCHEMBL20581718 | 0.75 | — | — | |
| SCHEMBL10698483 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL4886947 | 0.72 | — | — | |
| SCHEMBL8919030 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL25192455 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985373-A | New method for preparing (R)-1,2-di-fatty acid glycerol phosphatidyl glyceride | 江苏东南纳米材料有限公司 | 2016-10-05 | — | — | CN | claimed |
| CN-117916374-A | Oligonucleotide-based delivery vehicles for oligonucleotide agents and methods of use thereof | 中美瑞康核酸技术(南通)研究院有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-114516896-A | Artificial deoxyribose with hypoxia microenvironment response and application thereof | 上海交通大学医学院附属仁济医院 | 2022-05-20 | — | — | CN | disclosed |
| US-10125217-B2 | Method for producing polyether carbonate polyols | COVESTRO DEUTSCHLAND AG (DE) | 2018-11-13 | — | — | US | disclosed |
| US-10040901-B2 | Method for producing polyether carbonate polyols | COVESTRO DEUTSCHLAND AG (DE) | 2018-08-07 | — | — | US | disclosed |
| US-20170137569-A1 | Method for Producing Polyether Carbonate Polyols | COVESTRO DEUTSCHLAND AG (DE) | 2017-05-18 | — | — | US | disclosed |
| CN-105985373-A | New method for preparing (R)-1,2-di-fatty acid glycerol phosphatidyl glyceride | 江苏东南纳米材料有限公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-105985373-A | New method for preparing (R)-1,2-di-fatty acid glycerol phosphatidyl glyceride | 江苏东南纳米材料有限公司 | 2016-10-05 | — | — | CN | disclosed |
| US-20160264727-A1 | METHOD FOR PRODUCING POLYETHER CARBONATE POLYOLS | COVESTRO DEUTSCHLAND AG (DE) | 2016-09-15 | — | — | US | disclosed |
| EP-1809332-B1 | COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS | ONCOLOGIC INC (US) | 2011-12-14 | — | — | EP | disclosed |
| US-20030064483-A1 | Method of nucleic acid sequencing | DUKE UNIVERSITY. | 2003-04-03 | — | — | US | disclosed |
| US-6376178-B1 | INTRODUCING INTO CELL DNA SEQUENCE ENCODING PROTEIN, WHICH DNA SEQUENCE COMPRISES BORONATED NUCLEOTIDE, UNDER CONDITIONS SUCH THAT DNA SEQUENCE IS EXPRESSED AND PROTEIN THEREBY PRODUCED | DUKE UNIVERSITY | 2002-04-23 | — | — | US | disclosed |
| EP-1174434-A1 | Phosphonic acid derivative having inhibitory activity against carboxypeptidase B | MEIJI SEIKA KAISHA LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| EP-1152004-A1 | PHOSPHONIC ACID DERIVATIVES HAVING CARBOXYPEPTIDASE B INHIBITORY ACTIVITY | MEIJI SEIKA KAISHA LTD. (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6153737-A | OLIGONUCLEOTIDES HAVING IMPROVED TRANSFER ACROSS CELLULAR MEMBRANES; FOR ASSAYING DISEASE STATES IN ANIMALS; HAVING IMPROVED TRANSFER AND UPTAKE PROPERTIES FOR TREATMENT OF DISEASES THROUGH MODULATION OF ACTIVITY OF DNA AND RNA | ISIS PHARMACEUTICALS, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| US-5859231-A | SYNTHESIZING AN OLIGONUCLEOTIDE COMPRSING AN INTERNUCLEOTIDE H-PHOSPHATE DIESTER LINKAGE, REACTING DIESTER WITH BIS/TRIMETHYLSILYL/ACETAMIDE OR HALOGENATING AGENT TO FORM TRIESTER, BORONATING WITH AMINE BORANE; REACTING WITH AMMONIA | DUKE UNIVERSITY (US) | 1999-01-12 | — | — | US | disclosed |
| US-5683869-A | USE OF BORANO-SUBSTITUTED NUCLEOTIDE WHICH IS RESISTANT TO EXONUCLEASE DEGRADATION, AMPLIFICATION | DUKE UNIVERSITY (US) | 1997-11-04 | — | — | US | disclosed |
| US-5359053-A | Nucleic acid probes having nucleoside residue; usable with stringent hybridization conditions | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5332845-A | In DNA synthesis | CHIRON CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |
| US-5134066-A | Hybridization | MONSANTO COMPANY (US) | 1992-07-28 | — | — | US | disclosed |