⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28708765 | 0.96 | — | — | |
| Tetrahydrofuran SCHEMBL27452608 | 0.85 | — | — | |
| Dioxane SCHEMBL11798650 | 0.82 | — | — | |
| Tetrahydrofuran SCHEMBL17162024 | 0.82 | — | — | |
| SCHEMBL30466481 | 0.82 | ALDH1A1 (1.00) | — | |
| Tetrahydrofuran SCHEMBL130914 | 0.82 | — | — | |
| Tetrahydrofuran SCHEMBL6298732 | 0.82 | — | — | |
| SCHEMBL30432886 | 0.82 | ALDH1A1 (1.00) | — | |
| SCHEMBL3455441 | 0.82 | ALDH1A1 (1.00) | — | |
| Tetrahydrofuran SCHEMBL1982618 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527227-B | Preparation method of kalirazine | 四川弘远药业有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-113444124-B | Preparation method of tri (N, N-tetramethylene) phosphoramide | 河北圣泰材料股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-116715593-A | Optimized preparation method of dapoxetine hydrochloride and intermediate thereof | 北京悦康科创医药科技股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-116199605-A | Synthesis method of 5-chloro-2-hydroxy-dimethylbenzenesulfonamide | 上海睿腾医药科技有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-115073490-A | Preparation method of Ruogeli and intermediate thereof | 上海医药工业研究院 | 2022-09-20 | — | — | CN | claimed |
| CN-115043796-A | Method for preparing tetrahydrofuran diformamide and 2-hydroxyadipamide by hydrogenation of furan diformamide | 河北工业大学 | 2022-09-13 | — | — | CN | claimed |
| CN-112480106-B | Preparation method of Alvatripopa maleate impurity | 南京海纳医药科技股份有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-111533775-B | Ratio type leucine aminopeptidase fluorescent probe, preparation method thereof and application thereof in liver tumor cell targeted imaging | 绍兴文理学院 | 2022-02-25 | — | — | CN | claimed |
| CN-113527227-A | Preparation method of cariprazine | 成都弘达药业有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-113444124-A | Preparation method of tri (N, N-tetramethylene) phosphoramide | 石家庄圣泰化工有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-112175023-A | Preparation method of fatty alcohol acetyl chitobiose and fatty alcohol N-acetylglucosamine | 江南大学 | 2021-01-05 | — | — | CN | claimed |
| CN-111533775-A | Ratio type leucine aminopeptidase fluorescent probe, preparation method thereof and application thereof in liver tumor cell targeted imaging | 绍兴文理学院 | 2020-08-14 | — | — | CN | claimed |
| CN-110016024-A | A kind of key intermediate and its preparation method and application synthesizing CDK4/6 double inhibitor | 南京药石科技股份有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-106518708-B | The synthesis and application of new FXR activators | 中国药科大学 | 2018-02-16 | — | — | CN | claimed |
| CN-104926669-A | Preparation method of trans-4-dimethylaminocrotonic acid hydrochloride | JIANGSU HANSOH PHARMACEUTICAL | 2015-09-23 | — | — | CN | claimed |
| CN-104628584-A | High-purity dapoxetine preparation method suitable for industrialization | GUANGZHOU REGENEX CORP | 2015-05-20 | — | — | CN | claimed |
| CN-116655476-B | Preparation method of amino alcohol | 北京大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-115605525-B | Uretdione-containing compositions that crosslink at low temperatures | 科思创德国股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| US-4610821-A | CENTRAL NERVOUS SYSTEM, THYROTROPIN RELEASING HORMONE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | disclosed |
| US-4564609-A | NERVOUS SYSTEM DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |