SCHEMBL3455441

SCHEMBL3455441

C1CCOCCCCOCCCCOC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 1.00
TTR P02766 1/20 0.56
TSHR P16473 1/20 0.56
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL6364293 1.00 ALDH1A1 (1.00) ALDH1A1TTRTSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL6298732 1.00
Tetrahydrofuran SCHEMBL378197 1.00 ALDH1A1 (1.00) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL30432886 1.00 ALDH1A1 (1.00) ALDH1A1TTRTSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL1982618 1.00
Tetrahydrofuran SCHEMBL479 1.00
SCHEMBL30466481 1.00 ALDH1A1 (1.00) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL9576477 1.00 ALDH1A1 (1.00) ALDH1A1TTRTSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL130914 1.00
Tetrahydrofuran SCHEMBL5125765 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816537-B2 Process for the manufacture of epoxybutanol intermediates BASILEA PHARMACEUTICA AG (CH) 2010-10-19 US claimed
US-20090299073-A1 Process for the Manufacture of Epoxybutanol Intermediates MULLER MARC 2009-12-03 US claimed
EP-1954264-A2 PROCESS FOR THE MANUFACTURE OF EPOXYBUTANOL INTERMEDIATES Basilea Pharmaceutica AG (CH) 2008-08-13 EP claimed
WO-2007062542-A2 PROCESS FOR THE MANUFACTURE OF EPOXYBUTANOL INTERMEDIATES BASILEA PHARMACEUTICA AG (CH) 2007-06-07 WO claimed
US-12641944-B2 Light-emitting element and light-emitting device SHARP KABUSHIKI KAISHA (JP) 2026-05-26 US disclosed
US-20230090252-A1 LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SHARP KABUSHIKI KAISHA (JP) 2023-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12641944-B2 Light-emitting element and light-emitting device L1CAM, EPCAM, CRY1 ALDH1A1 100/4885TTR 3875/4885TSHR 2939/4885
US-20090299073-A1 Process for the Manufacture of Epoxybutanol Intermediates POR, CYP4A11, CYP1A1 ALDH1A1 259/4885TTR 1895/4885TSHR 842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.