SCHEMBL3566

SCHEMBL3566

O=c1[c]ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5862103 0.68
SCHEMBL7399100 0.68
SCHEMBL654054 0.67
SCHEMBL5908051 0.65
SCHEMBL582793 0.64
SCHEMBL19331457 0.64
SCHEMBL751581 0.63 HDAC8 (0.33)
SCHEMBL894826 0.62
SCHEMBL37815 0.62 KDM4E (0.54)
SCHEMBL21358015 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12154 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3074390-B1 AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS SIGNALCHEM LIFESCIENCES CORP (CA) 2020-07-08 EP claimed
EP-3397638-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Merial, Inc. (US) 2018-11-07 EP claimed
EP-3363803-A1 UREA PEPTOID BORIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USES THEREOF Peking University (CN) 2018-08-22 EP claimed
EP-2376447-B1 DIPEPTIDYL PEPTIDASE IV INHIBITORS ORCHID PHARMA LTD (IN) 2017-08-09 EP claimed
WO-2017116702-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL, INC. (US) 2017-07-06 WO claimed
US-20170050970-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE PHARMACYCLICS, INC. 2017-02-23 US claimed
US-20170001949-A1 NOVEL CANNABINOID RECEPTOR 2 (CB2) INVERSE AGONISTS AND THERAPEUTIC POTENTIAL FOR MULTIPLE MYELOMA AND OSTEOPOROSIS BONE DISEASES UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2017-01-05 US claimed
US-20150203496-A1 ALIPHATIC SPIROLACTAM CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME LLC 2015-07-23 US claimed
US-20150111914-A1 SPIROLACTAM CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME LLC 2015-04-23 US claimed
US-20150087641-A1 HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME CORP. 2015-03-26 US claimed
US-5744486-A Pyridinone thrombin inhibitors MERCK & CO., INC. (US) 1998-04-28 US claimed
EP-0835109-A1 PYRIDINONE-THROMBIN INHIBITORS Merck & Co., Inc. (US) 1998-04-15 EP claimed
WO-1997001338-A1 PYRIDINONE-THROMBIN INHIBITORS MERCK & CO., INC. (US) 1997-01-16 WO claimed
US-5569762-A Asymmetric synthesis of intermediates for retroviral protease inhibitor compounds AMERICAN CYANAMID COMPANY (US) 1996-10-29 US claimed
US-5428167-A Asymmetric synthesis of intermediates for retroviral protease inhibitor compounds AMERICAN CYANAMID COMPANY (US) 1995-06-27 US claimed
EP-0585383-A4 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORP (US) 1994-08-17 EP claimed
EP-0602306-A1 Retroviral protease inhibitors AMERICAN CYANAMID COMPANY (US) 1994-06-22 EP claimed
EP-0585383-A1 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1994-03-09 EP claimed
WO-1992020651-A2 N-(HETEROARYL)-IMIDAZOLYL-ALKENOIC ACIDS SMITHKLINE BEECHAM CORPORATION (US) 1992-11-26 WO claimed
EP-0492136-A2 Retroviral protease inhibitors derived from 3-chloro-2-chloromethyl-1-propene AMERICAN CYANAMID COMPANY (US) 1992-07-01 EP claimed