⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358015 | 0.96 | — | — | |
| Trifluoroacetic Acid SCHEMBL30018844 | 0.77 | L3MBTL1 (0.40) | — | |
| SCHEMBL8797058 | 0.74 | — | — | |
| SCHEMBL3907210 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL6186451 | 0.68 | — | — | |
| SCHEMBL3848 | 0.67 | — | — | |
| SCHEMBL24625410 | 0.65 | KDM4E (0.68) | — | |
| SCHEMBL21358014 | 0.65 | LMNA (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL7957885 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL4436012 | 0.65 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021049628-A1 | P2X4 RECEPTOR ANTAGONIST | 日本ケミファ株式会社 | 2021-03-18 | — | — | WO | claimed |
| EP-1869041-A1 | TETRAHYDRO-PYRIDOAZEPIN-8-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA | Warner-Lambert Company LLC (US) | 2007-12-26 | — | — | EP | claimed |
| WO-2006103559-A1 | TETRAHYDRO-PYRIDOAZEPIN-8-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA | WARNER-LAMBERT COMPANY LLC (US) | 2006-10-05 | — | — | WO | claimed |
| CN-114072397-B | Heteroaryl aminopyrimidinamide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240140983-A1 | SINGLE STRANDED DNA ENZYME INHIBITORS | MASSEY UNIVERSITY (NZ) | 2024-05-02 | — | — | US | disclosed |
| US-20240124910-A1 | RIBOSOME-MEDIATED POLYMERIZATION OF NOVEL CHEMISTRIES | NORTHWESTERN UNIVERSITY | 2024-04-18 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| WO-2022162536-A1 | SINGLE STRANDED DNA ENZYME INHIBITORS | MASSEY UNIVERSITY (NZ) | 2022-08-04 | — | — | WO | disclosed |
| WO-2021049628-A1 | P2X4 RECEPTOR ANTAGONIST | 日本ケミファ株式会社 | 2021-03-18 | — | — | WO | disclosed |
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| EP-1326183-A1 | Method for silico screening of molecules | SYNT:EM S.A. (FR) | 2003-07-09 | — | — | EP | disclosed |
| EP-0794194-B1 | A process for the preparation of 2'-deoxy-2'-halocoformycins or stereoisomers thereof | ZAIDAN HOJIN BISEIBUTSU (JP) | 2001-12-12 | — | — | EP | disclosed |
| CN-1235602-A | 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic urea useful as HIV protease inhibitors | DU PONT MERCK PHARMA (US) | 1999-11-17 | — | — | CN | disclosed |
| US-5831072-A | Process for the preparation of 2'-deoxy-2'-halocoformycins or steroisomers thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0794194-A1 | A process for the preparation of 2'-deoxy-2'-halocoformycins or stereoisomers thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0065324-A1 | 1,3-Diazepine compounds | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1982-11-24 | — | — | EP | disclosed |
| EP-0034424-A2 | Seven-membered ring compounds as inhibitors of cytidine deaminase | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1981-08-26 | — | — | EP | disclosed |
| WO-1981002164-A1 | SEVEN-MEMBERED RING COMPOUNDS AS INHIBITORS OF CYTIDINE DEAMINASE | US COMMERCE (US) | 1981-08-06 | — | — | WO | disclosed |
| US-4275057-A | CANCER AND ANTITUMOR DRUG RESEARCH | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1981-06-23 | — | — | US | disclosed |