SCHEMBL356732

SCHEMBL356732

COC/C=C(/C)CCC=C(C)C

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.62
ALOX15 P16050 3/20 0.62
ALDH1A1 P00352 2/20 0.62
MEN1 O00255 2/20 0.58
CYP3A4 P08684 2/20 0.58
MAPT P10636 2/20 0.56
UGT1A1 P22309 1/20 0.56
FNTA P49354 5/20 0.54
FNTB P49356 3/20 0.54
PGGT1B P53609 2/20 0.54
SQLE Q14534 3/20 0.54
KDM4E B2RXH2 1/20 0.50
GGPS1 O95749 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114886 1.00 KMT2A (0.62) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL114887 1.00 KMT2A (0.62) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL11617759 0.98 KMT2A (0.67) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL15980322 0.98 KMT2A (0.67) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL12967956 0.98 KMT2A (0.67) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL1704911 0.98 KMT2A (0.67) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL15980978 0.98 KMT2A (0.67) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL15980982 0.98 KMT2A (0.67) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL10127135 0.98 KMT2A (0.67) KMT2AALOX15ALDH1A1MEN1CYP3A4
SCHEMBL11039524 0.86 SQLE (0.54) KMT2AALOX15ALDH1A1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3087112-B1 PROCESSES TO IMPROVE REACTOR STABILITY FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS USING ASYMMETRICAL POLYENES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-01-30 EP disclosed
US-9796650-B2 Inhibitor combination for lithium salt-catalyzed transesterification process and method for removing lithium salt DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-24 US disclosed
US-9751964-B2 Processes to improve reactor stability for the preparation of ethylene-based polymers using asymmetrical polyenes DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-05 US disclosed
US-9718906-B2 Processes to form ethylene-based polymers using asymmetrical polyenes DOW GLOBAL TECHNOLOGIES LLC (US) 2017-08-01 US disclosed
US-20160304643-A1 PROCESSES TO IMPROVE REACTOR STABILITY FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS USING ASYMMETRICAL POLYENES DOW GLOBAL TECHNOLOGIES LLC 2016-10-20 US disclosed
US-20160297736-A1 Inhibitor Combination for Lithium Salt-Catalyzed Transesterification Process and Method for Removing Lithium Salt DOW GLOBAL TECHNOLOGIES LLC 2016-10-13 US disclosed
US-20150197590-A1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-16 US disclosed
WO-2015099915-A1 INHIBITOR COMBINATION FOR LITHIUM SALT-CATALYZED TRANSESTERIFICATION PROCESS AND METHOD FOR REMOVING LITHIUM SALT DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-02 WO disclosed
EP-2595642-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS The Procter and Gamble Company (US) 2013-05-29 EP disclosed
WO-2012012385-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2012-01-26 WO disclosed
US-20120014883-A1 Compositions Comprising Derivatives Of Essential Oil Compounds And Use In Personal Care Products THE PROCTER & GAMBLE COMPANY 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160297736-A1 Inhibitor Combination for Lithium Salt-Catalyzed Transesterification Process and Method for Removing Lithium Salt ADH1C, ADH1A, MAP2K1 KMT2A 862/4885ALOX15 301/4885ALDH1A1 347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.