Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.61 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099146 | 0.86 | EPHX2 (0.63) | KMT2AHPGDEPHX2NR1H4MEN1 | |
| SCHEMBL5177709 | 0.86 | GAA (0.74) | KMT2AHPGDEPHX2NR1H4MEN1 | |
| SCHEMBL5272168 | 0.85 | KMT2A (1.00) | KMT2AHPGDMEN1ERCC1ERCC4 | |
| SCHEMBL5178619 | 0.85 | GAA (0.54) | KMT2AHPGDEPHX2NR1H4MEN1 | |
| SCHEMBL17656854 | 0.84 | KMT2A (0.79) | KMT2AHPGDMEN1ERCC1ERCC4 | |
| SCHEMBL5177358 | 0.84 | KDM4E (0.60) | KMT2AHPGDEPHX2NR1H4MAPK1 | |
| SCHEMBL5175853 | 0.82 | RAB9A (0.74) | KMT2AHPGDMEN1CYP2C19ALDH1A1 | |
| SCHEMBL1695641 | 0.82 | KMT2A (0.66) | KMT2AHPGDMEN1ERCC1ERCC4 | |
| SCHEMBL4641618 | 0.81 | EPHX2 (0.67) | EPHX2NR1H4 | |
| SCHEMBL29754911 | 0.81 | KMT2A (0.53) | KMT2AHPGDEPHX2NR1H4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |