Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 13/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | BLVRB | P30043 | 1/20 | 0.59 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331587 | 0.89 | XDH (0.64) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3379629 | 0.89 | KDM4E (0.65) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523320 | 0.87 | RAB9A (0.67) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523322 | 0.87 | XDH (0.63) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL1331619 | 0.86 | XDH (0.66) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL1357282 | 0.85 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523350 | 0.84 | XDH (0.65) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL1359563 | 0.83 | XDH (0.58) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523289 | 0.83 | XDH (0.64) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL3384040 | 0.83 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816558-B2 | Triarylcarboxylic acid derivative | ASTELLAS PHARMA INC. (JP) | 2010-10-19 | — | — | US | claimed |