SCHEMBL3569028

SCHEMBL3569028

Nc1c(Cl)c(F)nc(F)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6314564 0.88 MEN1 (0.35) MEN1GAAKMT2ATDP1
SCHEMBL4852202 0.86 MEN1 (0.42) MEN1GAAKMT2A
SCHEMBL31042956 0.82 IDO1 (0.34)
SCHEMBL8409269 0.82 TDP1 (0.33) TDP1
SCHEMBL5941062 0.82 TDP1 (0.33) TDP1
SCHEMBL28691609 0.80 TDP1 (0.32) TDP1
Potassium SCHEMBL29368593 0.80 TDP1 (0.32) TDP1
SCHEMBL7172468 0.78 MEN1 (0.33) MEN1GAAKMT2ATDP1
SCHEMBL9787166 0.76 MEN1 (0.32) MEN1GAAKMT2A
SCHEMBL8986433 0.75 TDP1 (0.66) GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735579-A Pyrazole amide derivative, preparation method thereof and application of pyrazole amide derivative as anti-liver cancer drug 安徽医科大学第二附属医院 2025-04-01 CN claimed
CN-106008333-A Preparation method of 4-amino-3, 5-dichloro-6-fluoro-2-ethyl oxy-acetate pyridine 四川福思达生物技术开发有限责任公司 2016-10-12 CN claimed
CN-106008334-A Preparation process of 4-amino-3, 5-dichloro-6-fluoro-2-ethyl oxy-acetate pyridine 四川福思达生物技术开发有限责任公司 2016-10-12 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
US-4976946-A Solvent extraction by using N,N-dialkylamide or acetonitrile solvent THE DOW CHEMICAL COMPANY (US) 1990-12-11 US claimed
EP-4658647-A1 TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS UCB Biopharma SRL (BE) 2025-12-10 EP disclosed
CN-120349278-A Flucarbazone Process for the preparation of intermediates 安徽农业大学 2025-07-22 CN disclosed
CN-119735579-A Pyrazole amide derivative, preparation method thereof and application of pyrazole amide derivative as anti-liver cancer drug 安徽医科大学第二附属医院 2025-04-01 CN disclosed
WO-2024160722-A1 TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS UCB Biopharma SRL (BE) 2024-08-08 WO disclosed
CN-117185994-A Synthesis method of fluroxypyr intermediate 利尔化学股份有限公司 2023-12-08 CN disclosed
CN-113999169-B Preparation method of fluroxypyr-meptyl 江苏中旗科技股份有限公司 2023-04-07 CN disclosed
CN-113999169-B Preparation method of fluroxypyr-meptyl 江苏中旗科技股份有限公司 2023-04-07 CN disclosed
EP-0576143-A2 Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group ZENECA LIMITED (GB) 1993-12-29 EP disclosed
EP-0576143-A2 Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group ZENECA LIMITED (GB) 1993-12-29 EP disclosed
EP-0254063-B1 PROCESS FOR THE RECOVERY OF AMMONIA AND FLUORIDE VALUES FROM AMMONIUM FLUORIDE SOLUTIONS DOWELANCO (US) 1991-09-04 EP disclosed
US-4976946-A Solvent extraction by using N,N-dialkylamide or acetonitrile solvent THE DOW CHEMICAL COMPANY (US) 1990-12-11 US disclosed
EP-0254063-A2 Process for the recovery of ammonia and fluoride values from ammonium fluoride solutions DOWELANCO (US) 1988-01-27 EP disclosed
US-4713231-A Process for the recovery of ammonia and fluoride values from ammonium fluoride solutions THE DOW CHEMICAL COMPANY (US) 1987-12-15 US disclosed
EP-0192287-A2 Process for the preparation of fluorinated pyridines SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-08-27 EP disclosed