SCHEMBL8409269

SCHEMBL8409269

Nc1c(Cl)c(O)nc(F)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28691609 0.98 TDP1 (0.32) TDP1
Potassium SCHEMBL29368593 0.98 TDP1 (0.32) TDP1
SCHEMBL3569028 0.82 MEN1 (0.37) TDP1
SCHEMBL8735002 0.75 CES2 (0.31)
SCHEMBL11614099 0.75 TDP1 (0.50) TDP1
SCHEMBL6314564 0.72 MEN1 (0.35) TDP1
SCHEMBL31042956 0.71 IDO1 (0.34)
SCHEMBL5941062 0.71 TDP1 (0.33) TDP1
SCHEMBL4852202 0.70 MEN1 (0.42)
SCHEMBL8735394 0.70 CES2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0441457-B1 Preparation of higher alkyl esters of carboxylic acids DOWELANCO (US) 1996-06-05 EP claimed
US-5214150-A Preparation of higher alkylesters of carboxylic acids DOWELANCO (US) 1993-05-25 US claimed
EP-0441457-A2 Preparation of higher alkyl esters of carboxylic acids DOWELANCO (US) 1991-08-14 EP claimed
US-4976946-A Solvent extraction by using N,N-dialkylamide or acetonitrile solvent THE DOW CHEMICAL COMPANY (US) 1990-12-11 US claimed
US-5965487-A STABLE, HOMOGENEOUS AQUEOUS CONCENTRATE COMPRISING AN ALKALI METAL OR AMINE SALT OF A HERBICIDAL SALT, E.G., A SALT OF 2,4-D, MCPA, AND A WATER-INSOLUBLE ESTER OF FLUROXYPYR OR TRICLOPYR HERBICIDE; SOLVENT-FREE; SPRAYABLE DOW AGROSCIENCES LLC (US) 1999-10-12 US disclosed
EP-0814662-B1 MIXED HERBICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 1999-07-14 EP disclosed
US-5869681-A PREPARING TRIAZOLINONE INTERMEDIATE BY HEATING HYDROCARBYLOXYCARBONYL-ISOSEMICARBAZIDE TO CYCLIZE BAYER AKTIENGESELLSCHAFT (DE) 1999-02-09 US disclosed
EP-0647096-B1 AGRICULTURAL FORMULATIONS CONTAINING LIQUID ESTERS OF FLUROXYPYR DOWELANCO (US) 1998-08-05 EP disclosed
US-5750718-A CHEMICAL INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1998-05-12 US disclosed
EP-0814662-A1 MIXED HERBICIDAL COMPOSITIONS DOWELANCO LIMITED (US) 1998-01-07 EP disclosed
US-5693663-A PESTICIDES; HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
US-5677449-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
EP-0647096-A1 AGRICULTURAL FORMULATIONS CONTAINING LIQUID ESTERS OF FLUROXYPYR DOWELANCO (US) 1995-04-12 EP disclosed
US-5374603-A Herbicides DOWELANCO (US) 1994-12-20 US disclosed
WO-1994024866-A1 AGRICULTURAL FORMULATIONS DOWELANCO (US) 1994-11-10 WO disclosed
US-5214150-A Preparation of higher alkylesters of carboxylic acids DOWELANCO (US) 1993-05-25 US disclosed
US-5214150-A Preparation of higher alkylesters of carboxylic acids DOWELANCO (US) 1993-05-25 US disclosed
EP-0441457-A2 Preparation of higher alkyl esters of carboxylic acids DOWELANCO (US) 1991-08-14 EP disclosed
EP-0441457-A2 Preparation of higher alkyl esters of carboxylic acids DOWELANCO (US) 1991-08-14 EP disclosed
US-4976946-A Solvent extraction by using N,N-dialkylamide or acetonitrile solvent THE DOW CHEMICAL COMPANY (US) 1990-12-11 US disclosed