Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | FABP2 | P12104 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572707 | 0.92 | CCR9 (0.42) | LPAR1LPAR5C5AR1LPAR2ALDH1A1 | |
| SCHEMBL3577662 | 0.89 | LPAR1 (0.43) | LPAR1LPAR5C5AR1LPAR2ALDH1A1 | |
| SCHEMBL3569645 | 0.87 | CCR9 (0.43) | LPAR1LPAR5C5AR1LPAR2ALDH1A1 | |
| SCHEMBL3580876 | 0.85 | LPAR1 (0.36) | LPAR1LPAR5C5AR1ALDH1A1GAA | |
| SCHEMBL3577563 | 0.85 | NLRP3 (0.42) | LPAR1LPAR5C5AR1LPAR2ALDH1A1 | |
| SCHEMBL3580698 | 0.84 | C5AR1 (0.44) | C5AR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL3577159 | 0.83 | C5AR1 (0.42) | LPAR1LPAR5C5AR1LPAR2ALDH1A1 | |
| SCHEMBL3571491 | 0.83 | C5AR1 (0.42) | LPAR1LPAR5C5AR1LPAR2ALDH1A1 | |
| SCHEMBL3584106 | 0.83 | LPAR1 (0.59) | LPAR1LPAR5C5AR1LPAR2 | |
| SCHEMBL3584209 | 0.82 | C5AR1 (0.45) | LPAR1LPAR5C5AR1LPAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |