⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783652 | 0.80 | — | — | |
| SCHEMBL29234423 | 0.77 | PDPK1 (0.38) | — | |
| Potassium SCHEMBL30965126 | 0.77 | PDPK1 (0.38) | — | |
| SCHEMBL1043235 | 0.72 | — | — | |
| SCHEMBL221096 | 0.72 | — | — | |
| SCHEMBL329345 | 0.72 | — | — | |
| SCHEMBL29387154 | 0.72 | — | — | |
| SCHEMBL943525 | 0.72 | APOBEC3G (0.33) | — | |
| SCHEMBL3531209 | 0.72 | CA2 (0.61) | — | |
| SCHEMBL330891 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102557971-B | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2015-06-17 | — | — | CN | claimed |
| US-8841296-B2 | Substituted 1, 4-dioxa-8-azaspiro[4,5]decanes useful as fungicides and a process for the preparation thereof | Council of Scientific and Industrial Research, Anusandhan Bhawan, Rafi Marg (IN) | 2014-09-23 | — | — | US | claimed |
| CN-102796050-B | Cdc42 inhibitor and application thereof | ANGKE BIOLOG MEDICLA TECHNOLOGY SUZHOU CO LTD | 2014-07-23 | — | — | CN | claimed |
| EP-1653960-A4 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN INC (US) | 2008-11-26 | — | — | EP | claimed |
| EP-1653960-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN INC. (US) | 2006-05-10 | — | — | EP | claimed |
| US-20050215526-A1 | Melanin concentrating hormone receptor antagonist | AMGEN, INC. | 2005-09-29 | — | — | US | claimed |
| WO-2005019167-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| CN-110526907-A | Benzoxazine ketones derivant and its application | UNIV SICHUAN | 2019-12-03 | — | — | CN | disclosed |
| CN-110291652-A | Organic electroluminescent element | 学校法人关西学院 | 2019-09-27 | — | — | CN | disclosed |
| CN-110249442-A | Organic electroluminescent element | 学校法人关西学院 | 2019-09-17 | — | — | CN | disclosed |
| CN-106458994-B | Biaryl kinase inhibitor | 百时美施贵宝公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-105330646-B | A kind of preparation method of antineoplastic maleic acid linatinib | 上海勋和医药科技有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-105164142-B | Mannose Derivatives for the Treatment of Bacterial Infections | 沃泰克斯药物股份有限公司 | 2019-03-08 | — | — | CN | disclosed |
| EP-1653960-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN INC. (US) | 2006-05-10 | — | — | EP | disclosed |
| US-20050215526-A1 | Melanin concentrating hormone receptor antagonist | AMGEN, INC. | 2005-09-29 | — | — | US | disclosed |
| WO-2005019167-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| US-4701565-A | REACTING ALCOHOL WITH ORGANIC SULFONYL HALIDE TO FORM SULFONATE, REACTING SULFONATE WITH A PHENOL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-10-20 | — | — | US | disclosed |
| US-4211548-A | Esters of N-phosphinothioylmethylglycine and herbicidal method | MONSANTO COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4211732-A | N-Carbobenzoxy-N-phosphinothioylmethylgylcine esters | MONSANTO COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4195983-A | HERBICIDES | MONSANTO COMPANY (US) | 1980-04-01 | — | — | US | disclosed |