Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 15/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 8/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239550 | 0.98 | FDPS (0.41) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL4982879 | 0.98 | FDPS (0.41) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL2120550 | 0.77 | FDPS (0.45) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL28340215 | 0.76 | FDPS (0.44) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL27496575 | 0.75 | FDPS (0.41) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL256372 | 0.74 | GRM5 (0.46) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL5578780 | 0.74 | FDPS (0.42) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL5633 | 0.74 | FDPS (0.42) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL840562 | 0.74 | FDPS (0.46) | FDPSHDAC1HDAC6CYP1A2CYP2C9 | |
| SCHEMBL10664500 | 0.74 | FDPS (0.46) | FDPSHDAC1HDAC6CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112245440-A | Use of tocotrienol derivatives | 北京蔚蓝之源医药科技有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-109232210-A | A method of it is synthesized using micro passage reaction to alkylacetophenone | 濮阳市欧亚化工科技有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-108484605-A | A kind of chloro- 9- of 2- amino -6-（4- acetoxy-3s-acetyl-o-methyl butyl）The preparation method of purine | 上药康丽（常州）药业有限公司 | 2018-09-04 | — | — | CN | claimed |
| EP-2663309-B1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | INFINITY PHARMACEUTICALS INC (US) | 2017-03-15 | — | — | EP | claimed |
| CN-103648499-B | Processes for preparing isoquinolinones and solid forms of isoquinolinones | 无限药品股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| US-9290497-B2 | Processes for preparing isoquinolinones and solid forms of isoquinolinones | INFINITY PHARMACEUTICALS, INC. (US) | 2016-03-22 | — | — | US | claimed |
| CN-104031048-B | A kind of β-chloroethylnitrosoureas compound and preparation method and use thereof | BEIJING UNIVERSITY OF TECHNOLOGY (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-105294761-A | Impurities of tenofovir disoproxil fumarate or tenofovir, and preparation method thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105153163-A | 2,9-disubstituted purine-6-amino hydroxamic acid HDAC (histone deacetylase) inhibitor, preparation method and application | UNIV SHANDONG | 2015-12-16 | — | — | CN | claimed |
| CN-103304601-B | Tenofovir disoproxil new synthetic process | Chengdu Fluorine Bio-tech Co., Ltd. (CN) | 2015-09-30 | — | — | CN | claimed |
| EP-1628685-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2006-03-01 | — | — | EP | claimed |
| EP-1617848-A2 | ANTI-CANCER PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-01-25 | — | — | EP | claimed |
| WO-2005023811-A1 | PROCESS FOR THE PREPARATION OF (1S, 4R) -CIS-4-‘2-AMINO-6CHLORO-9H-PURIN-9-YL!-2-CYCLOPENTENE-1-METHANOL | GLAXO GROUP LIMITED (GB) | 2005-03-17 | — | — | WO | claimed |
| WO-2004096286-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096235-A2 | ANTI-CANCER PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| EP-0861841-B1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS COMPANY (JP) | 2001-04-04 | — | — | EP | claimed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| CN-1226602-A | Fast culture media for mycobaterium tuberculosis and preparation thereof | LIU ZHAOYUN (CN) | 1999-08-25 | — | — | CN | claimed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | claimed |
| US-3939089-A | PEROXYSULFATE | TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) | 1976-02-17 | — | — | US | claimed |