SCHEMBL7787139

SCHEMBL7787139

In1cnc2cncnc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.42
HDAC1 Q13547 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
LTA4H P09960 1/20 0.36
CYP1A2 P05177 14/20 0.36
ALDH1A1 P00352 9/20 0.36
CYP3A4 P08684 9/20 0.36
TSHR P16473 8/20 0.36
CYP2C19 P33261 7/20 0.36
CYP2C9 P11712 7/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 1/20 0.36
HBB P68871 1/20 0.36
KMT2A Q03164 1/20 0.36
MKNK2 Q9HBH9 1/20 0.35
USP2 O75604 5/20 0.34
CLK4 Q9HAZ1 3/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120550 0.77 FDPS (0.45) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL28340215 0.76 FDPS (0.44) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL28779724 0.74 FDPS (0.42) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL10664500 0.74 FDPS (0.46) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL28763050 0.74 FDPS (0.46) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL357004 0.74 FDPS (0.42) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL5633 0.74 FDPS (0.42) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL840562 0.74 FDPS (0.46) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL5578780 0.74 FDPS (0.42) FDPSHDAC1HDAC6LTA4HCYP1A2
SCHEMBL30341176 0.74 GRM5 (0.46) FDPSHDAC1HDAC6LTA4HCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100490818-C Methods for treating hepatitis delta virus infection with beta-L-2' deoxy-uncleosides NOVARTIS AG (CH) 2009-05-27 CN claimed
WO-2023109870-A1 PYRAZOLOPYRIMIDINE COMPOUND AND USE THEREOF 上海壹迪生物技术有限公司 2023-06-22 WO disclosed
US-10915023-B2 Nitrogen heterocycle-containing monolayers on metal oxides for binding biopolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-02-09 US disclosed
US-20190137879-A1 NITROGEN HETEROCYCLE-CONTAINING MONOLAYERS ON METAL OXIDES FOR BINDING BIOPOLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-05-09 US disclosed
CN-108524505-A Method and composition for cell Proliferation associated disease 安吉奥斯医药品有限公司 2018-09-14 CN disclosed
CN-102985557-B Methods and compositions for cell proliferation-related disorders 安吉奥斯医药品有限公司 2018-06-15 CN disclosed
CN-103638522-A Methods of increasing lymphatic function GEN HOSPITAL CORP 2014-03-19 CN disclosed
CN-101120947-B Beta-l-2'-deoxy-nucleosides for the treatment of hepatitis b IDENIX PHARMACEUTICALS INC (US) 2010-11-24 CN disclosed
CN-1911237-B Beta - l-2'-deoxy-nucleosides for the treatment of hepatitis b IDENIX PHARMACEUTICALS INC (US) 2010-09-15 CN disclosed
CN-101148448-B Method for preparing N2-quinoline substituted purine derivative ZHEJIANG MEDICAL CO LTD XINCHANG PHARMACEUTICAL PLANT 2010-08-04 CN disclosed
CN-1911237-A Beta - l-2'-deoxy-nucleosides for the treatment of hepatitis b IDENIX CAYMAN LTD (KY) 2007-02-14 CN disclosed
CN-1268345-C Method of treating hepatitis delta viral infection UNIV GEORGETOWN (US) 2006-08-09 CN disclosed
CN-1257912-C beta-L-2' -deoxy-nucleosides for the treatment of hepatitis B IDENEX CAYMAN LTD (GB) 2006-05-31 CN disclosed
CN-1606983-A beta-L-2' -deoxy-nucleosides for the treatment of hepatitis B IDENIX CAYMAN LTD (KY) 2005-04-20 CN disclosed
CN-1478483-A Beta-L-2'-dioxidition-nucleoside for treating hepatitis B ŵ�������ҩ���޹�˾ 2004-03-03 CN disclosed
CN-1444483-A Methods of treating hepatitis delta virus infection with beta-L-2' -deoxynucleosides EDENNICKS CAYMAN CO LTD (KY) 2003-09-24 CN disclosed
CN-1431907-A Methods of treating hepatitis delta virus infection UNIV GEORGETOWN (US) 2003-07-23 CN disclosed
CN-1320128-A beta-L-2' -deoxy-nucleosides for the treatment of hepatitis B NORIVIO PHARMACEUTICALS LTD (FR) 2001-10-31 CN disclosed
JP-2001072680-A NEW METHOD FOR PRODUCING PURINE IODIDE DERIVATIVE EISAI CO LTD 2001-03-21 JP disclosed
JP-2001072680-A NEW METHOD FOR PRODUCING PURINE IODIDE DERIVATIVE EISAI CO LTD 2001-03-21 JP disclosed