SCHEMBL357024

SCHEMBL357024

CCCCCc1ccc(CO)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.65
ADRA2A P08913 2/20 0.65
ADORA3 P0DMS8 2/20 0.65
TACR2 P21452 2/20 0.65
SLC6A2 P23975 2/20 0.65
SLC6A4 P31645 2/20 0.65
SLC6A3 Q01959 2/20 0.65
ALDH1A1 P00352 2/20 0.65
KDM4E B2RXH2 1/20 0.65
LMNA P02545 1/20 0.65
SHBG P04278 1/20 0.65
TP53 P04637 1/20 0.65
CYP3A4 P08684 1/20 0.65
HSPD1 P10809 1/20 0.65
ADRB3 P13945 1/20 0.65
HTR2C P28335 1/20 0.65
HSPE1 P61604 1/20 0.65
HIF1A Q16665 1/20 0.65
TST Q16762 1/20 0.65
HSD17B10 Q99714 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358879 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL359592 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL176980 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL11031408 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL4297552 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL359570 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9600021 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL359311 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL7769065 0.98 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL10985836 0.94 RARB (0.62) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56138135-A None JP disclosed
EP-3569608-B1 OLIGOSACCHARIDE COMPOUND FOR INHIBITING ENDOGENOUS COAGULATION FACTOR X-ENZYME COMPLEX, AND PREPARATION METHOD THEREFOR AND USES THEREOF JIUZHITANG CO LTD (CN) 2026-05-20 EP disclosed
US-12280072-B2 Oligosaccharide compound for inhibiting intrinsic coagulation factor X-enzyme complex, and preparation method therefor and uses thereof JIUZHITANG CO., LTD. (CN) 2025-04-22 US disclosed
CN-119219629-A N-benzyl imidazopyridine derivative and preparation method and application thereof 中国药科大学 2024-12-31 CN disclosed
US-20240041918-A1 Oligosaccharide Compound for Inhibiting Intrinsic Coagulation Factor X-Enzyme Complex, and Preparation Method Therefor and Uses Thereof JIUZHITANG CO., LTD. (CN) 2024-02-08 US disclosed
US-11840601-B2 Composition of alkoxysilyl-functionalized epoxy resin and composite thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2023-12-12 US disclosed
US-11833169-B2 2023-12-05 US disclosed
CN-108285498-B Oligosaccharide compound for inhibiting endogenous coagulation factor X enzyme complex and preparation method and application thereof 九芝堂股份有限公司 2021-11-23 CN disclosed
US-20200254003-A1 OLIGOSACCHARIDE COMPOUND FOR INHIBITING INTRINSIC COAGULATION FACTOR X-ENZYME COMPLEX, AND PREPARATION METHOD THEREFOR AND USES THEREOF MUDANJIANG YOUBO PHARMACEUTICAL CO., LTD. (CN) 2020-08-13 US disclosed
EP-3569608-A1 OLIGOSACCHARIDE COMPOUND FOR INHIBITING ENDOGENOUS COAGULATION FACTOR X-ENZYME COMPLEX, AND PREPARATION METHOD THEREFOR AND USES THEREOF Jiuzhitang Co., Ltd. (CN) 2019-11-20 EP disclosed
US-6090961-A Method for producing titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-07-18 US disclosed
EP-0992479-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-12 EP disclosed
EP-0970964-A2 Method for producing titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-01-12 EP disclosed
US-5180521-A Liquid crystal displays, cyclohexyl nitriles MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1993-01-19 US disclosed
EP-0224579-A1 SMECTIC LIQUID CRYSTALLINE PHASES. MERCK PATENT GMBH (DE) 1987-06-10 EP disclosed
WO-1986007085-A1 SMECTIC LIQUID CRYSTALLINE PHASES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-12-04 WO disclosed
EP-0058512-B1 LIQUID CRYSTAL COMPOUNDS EXHIBITING A SMALL DIELECTRIC ANISOTROPY AND LIQUID CRYSTAL MATERIALS AND DEVICES INCORPORATING SUCH COMPOUNDS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1986-01-15 EP disclosed
US-4556745-A BICYCOL(2.2.2) OCATANE RING THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1985-12-03 US disclosed
EP-0058512-A1 Liquid crystal compounds exhibiting a small dielectric anisotropy and liquid crystal materials and devices incorporating such compounds The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1982-08-25 EP disclosed
JP-S56138135-A LIQUID CRYSTAL COMPOUND HITACHI LTD 1981-10-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280072-B2 Oligosaccharide compound for inhibiting intrinsic coagulation factor X-enzyme complex, and preparation method therefor and uses thereof F11, F8, HABP2 ESR1 4581/4885ADRA2A 4837/4885ADORA3 4561/4885
US-20200254003-A1 OLIGOSACCHARIDE COMPOUND FOR INHIBITING INTRINSIC COAGULATION FACTOR X-ENZYME COMPLEX, AND PREPARATION METHOD THEREFOR AND USES THEREOF F11, F8, HABP2 ESR1 4581/4885ADRA2A 4837/4885ADORA3 4561/4885
US-20240041918-A1 Oligosaccharide Compound for Inhibiting Intrinsic Coagulation Factor X-Enzyme Complex, and Preparation Method Therefor and Uses Thereof F11, F8, HABP2 ESR1 4581/4885ADRA2A 4837/4885ADORA3 4561/4885
US-11833169-B2 SERPINC1, HPSE, HABP2 ESR1 4840/4885ADRA2A 4514/4885ADORA3 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.