Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385012 | 0.86 | MEN1 (0.54) | MAOBBCHELCKMAOANR4A2 | |
| SCHEMBL9189685 | 0.84 | NPC1 (0.57) | MAOBBCHEAPP | |
| SCHEMBL9189089 | 0.84 | TP53 (0.47) | MAOBLCKLMNAAPP | |
| SCHEMBL15690119 | 0.83 | NPC1 (0.51) | MAOBMAOAFFAR1 | |
| SCHEMBL6749775 | 0.83 | ALOX5 (0.67) | MAOBBCHELCKMAOAALOX5 | |
| SCHEMBL852434 | 0.83 | MAOB (0.57) | MAOBBCHECYP4F2CYP4A11LCK | |
| SCHEMBL6209659 | 0.83 | MAOB (0.57) | MAOBBCHECYP4F2CYP4A11LCK | |
| SCHEMBL538272 | 0.83 | MAOB (0.69) | MAOBBCHECYP4F2CYP4A11LCK | |
| SCHEMBL30344886 | 0.83 | MAOB (0.69) | MAOBBCHECYP4F2CYP4A11LCK | |
| SCHEMBL15688057 | 0.82 | DRD2 (0.51) | MAOBBCHEMAOAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344940-B | BTK inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-108066220-A | A kind of fragrant profit moisturizer and preparation method thereof | 湖北瑞晟生物有限责任公司 | 2018-05-25 | — | — | CN | disclosed |
| CN-107344940-A | BTK inhibitor and application thereof | 广东东阳光药业有限公司 | 2017-11-14 | — | — | CN | disclosed |
| CN-103655306-A | Antisepsis and anti-inflammation toothpaste without preservative and preparation method thereof | QINGDAO HIFUN MARINE BIOLOG TECHNOLOGY CO LTD | 2014-03-26 | — | — | CN | disclosed |
| US-20100168106-A1 | Amino-5-(5-membered)heteroarylimidazolone Compounds And The Use Thereof For Beta-secretase Modulation | WYETH LLC (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168106-A1 | Amino-5-(5-membered)heteroarylimidazolone Compounds And The Use Thereof For Beta-secretase Modulation | WYETH LLC (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168106-A1 | Amino-5-(5-membered)heteroarylimidazolone Compounds And The Use Thereof For Beta-secretase Modulation | WYETH LLC (US) | 2010-07-01 | — | — | US | disclosed |
| US-7705030-B2 | Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation | WYETH LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705030-B2 | Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation | WYETH LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705030-B2 | Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation | WYETH LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-5559144-A | LIPOXYGENASE INHIBITORS, INHIBITORS OF BIOSYNTHESIS OF LEUKOTRIENES | ABBOTT LABORATORIES (US) | 1996-09-24 | — | — | US | disclosed |
| US-5476873-A | Inhibit biosynthesis of leukotrienes | ABBOTT LABORATORIES (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0476658-B1 | 1-Phenyl-3-phenyl-2-propyne-1-ones | MERRELL DOW PHARMA (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5446068-A | Antiinflammatory agent | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0540673-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| US-5248825-A | Aromatic ketones containing triple bond | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0540673-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY. | ABBOTT LAB (US) | 1993-05-12 | — | — | EP | disclosed |
| CN-1059901-A | CALCIUM UPTAKE INHIBITORS | MERRELL DOW PHARMA (US) | 1992-04-01 | — | — | CN | disclosed |
| EP-0476658-A1 | 1-Phenyl-3-phenyl-2-propyne-1-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1992001682-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1992-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168106-A1 | Amino-5-(5-membered)heteroarylimidazolone Compounds And The Use Thereof For Beta-secretase Modulation | BACE1, BACE2, APP | MAOB 779/4885BCHE 19/4885CYP4F2 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.