SCHEMBL35725

SCHEMBL35725

CC(C)OCCOC(=O)C=CC#N

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.37
HCAR2 Q8TDS4 5/20 0.35
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
TSHR P16473 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1603097 0.80 TDP1 (0.48) ATMHCAR2LMNATDP1ALDH1A1
SCHEMBL487322 0.79 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3791086 0.79 TSHR (0.50) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3786038 0.79 TSHR (0.50) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1344016 0.77 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL167356 0.77 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL21999255 0.77 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL462001 0.76 TSHR (0.48) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11809880 0.76 ATM (0.38) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL35691 0.76 LMNA (0.38) ATMHCAR2LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274628-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS Adhezion Biomedical, LLC (US) 2023-11-15 EP claimed
CN-117062636-A Catheter securement compositions and methods 艾德合森生物医药有限责任公司 2023-11-14 CN claimed
EP-3513744-B1 MESH DISPENSER ETHICON INC (US) 2022-11-16 EP claimed
US-11413370-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2022-08-16 US claimed
US-20220218951-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS PROVIDING SIGNIFICANTLY STRONG SECUREMENT, WATER RESISTANT SEAL, EFFECTIVE HEMOSTATIS, AND ANTIBACTERIAL PROPERTIES AT AND AROUND VASCULAR ACCESS SITES H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. 2022-07-14 US claimed
WO-2022150498-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS ADHEZION BIOMEDICAL, LLC (US) 2022-07-14 WO claimed
US-20200315624-A1 Flexible Material Dispenser ETHICON INC (US) 2020-10-08 US claimed
US-10722688-B2 Device and liquid compositions for securing catheters having a rigid tapered tip ADHEZION BIOMEDICAL, LLC (US) 2020-07-28 US claimed
US-10434211-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2019-10-08 US claimed
EP-3513744-A1 MESH DISPENSER Ethicon, Inc. (US) 2019-07-24 EP claimed
WO-1997031598-A1 MONOMERIC COMPOSITIONS EFFECTIVE AS WOUND CLOSURE DEVICES CLOSURE MEDICAL CORPORATION (US) 1997-09-04 WO claimed
EP-0767819-A1 pH-MODIFIED BIOCOMPATIBLE MONOMER AND POLYMER COMPOSITIONS TRI-POINT MEDICAL CORPORATION (US) 1997-04-16 EP claimed
US-5582834-A APPLYING AN IN VIVO POLYMERIZABLE TISSUE ADHESIVE COMPRISING A FORMALDEHYDE SCAVENGER TRI-POINT MEDICAL, CORPORATION (US) 1996-12-10 US claimed
US-5575997-A CYANTOACRYLATES TRI-POINT MEDICAL CORPORATION (US) 1996-11-19 US claimed
EP-0727230-A2 Utilization of biocompatible adhesive/sealant materials for securing surgical devices ETHICON, INC. (US) 1996-08-21 EP claimed
US-5514371-A CYANOACRYLATES TRI-POINT MEDICAL L.P. (US) 1996-05-07 US claimed
US-5514372-A Biocompatible monomer and formaldehyde producing polymer compositions TRI-POINT MEDICAL L.P. (US) 1996-05-07 US claimed
WO-1996000760-A1 pH-MODIFIED BIOCOMPATIBLE MONOMER AND POLYMER COMPOSITIONS TRI-POINT MEDICAL CORPORATION (US) 1996-01-11 WO claimed
EP-0617973-A1 Biocompatible monomer and polymer compositions TRI-POINT MEDICAL CORPORATION (US) 1994-10-05 EP claimed
US-5328687-A Cyanoacrylate tissue adhesives, formaldehyde scavenger TRI-POINT MEDICAL L.P. (US) 1994-07-12 US claimed