SCHEMBL357271

SCHEMBL357271

CCCC(=O)Oc1ccc(OC)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.62
MAPT P10636 3/20 0.62
LMNA P02545 2/20 0.62
HSD17B10 Q99714 2/20 0.62
ALDH1A1 P00352 2/20 0.62
HTT P42858 1/20 0.62
BCL9 O00512 1/20 0.62
CTNNB1 P35222 1/20 0.62
GAA P10253 4/20 0.54
MEN1 O00255 3/20 0.52
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
RAB9A P51151 1/20 0.50
EGFR P00533 1/20 0.50
ERBB2 P04626 1/20 0.50
TP53 P04637 1/20 0.48
KDM4E B2RXH2 1/20 0.48
GLA P06280 1/20 0.48
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31329312 0.94 BCL9 (0.57) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL11023644 0.92 BCL9 (0.70) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL3498918 0.90 BCL9 (0.53) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL8631220 0.90 KMT2A (0.76) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL7500294 0.89 KMT2A (0.58) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL6836918 0.86 BCL9 (0.64) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL13557799 0.86 KMT2A (0.64) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL14984017 0.86 KMT2A (0.64) KMT2AMAPTLMNAHSD17B10ALDH1A1
Butane SCHEMBL2851843 0.85 KMT2A (0.59) KMT2AMAPTLMNAHSD17B10ALDH1A1
SCHEMBL28611141 0.85 PDGFRB (0.52) KMT2AMAPTLMNAHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700479-A Targeted prostate specific membrane antigen inhibitor, radioactive marker, preparation method and application thereof 原子高科股份有限公司 2024-03-15 CN claimed
US-20220112451-A1 BOURBON REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. 2022-04-14 US claimed
US-20220010248-A1 SCOTCH REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. 2022-01-13 US claimed
CN-113825409-A Whiskey imitation made from individual components 艾娃食品实验室有限公司 2021-12-21 CN claimed
US-20210340474-A1 WHISKEY REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. 2021-11-04 US claimed
EP-3860360-A1 SCOTCH REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. (US) 2021-08-11 EP claimed
EP-3860359-A1 WHISKEY REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. (US) 2021-08-11 EP claimed
EP-3755787-A1 MOSCATO WINE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. (US) 2020-12-30 EP claimed
EP-3755786-A1 ALCOHOLIC BEVERAGES PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. (US) 2020-12-30 EP claimed
WO-2020072555-A1 WHISKEY REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS AVA FOOD LABS, INC. (US) 2020-04-09 WO claimed
WO-2013176897-A2 COMPOSITION FOR REDUCTION OF TRPA1 AND TRPV1 SENSATIONS THE PROCTER & GAMBLE COMPANY (US) 2013-11-28 WO claimed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP claimed
CN-103153272-A Compositions comprising derivatives of essential oil compounds and use in personal care products PROCTER & GAMBLE 2013-06-12 CN claimed
CN-103140209-A Oral care compositions with improved flavor PROCTER & GAMBLE 2013-06-05 CN claimed
EP-2595642-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS The Procter and Gamble Company (US) 2013-05-29 EP claimed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO claimed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 US claimed
WO-2012012385-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2012-01-26 WO claimed
US-20120014883-A1 Compositions Comprising Derivatives Of Essential Oil Compounds And Use In Personal Care Products THE PROCTER & GAMBLE COMPANY 2012-01-19 US claimed
CN-101346073-A Compositions providing a sensation substantially similar to that provided by menthol CADBURY ADAMS USA LLC (US) 2009-01-14 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120082628-A1 Oral Care Compositions With Improved Flavor TRPA1, TAS2R40, TAS2R30 KMT2A 1953/4885MAPT 4044/4885LMNA 3584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.