SCHEMBL3573472

SCHEMBL3573472

O=S(=O)(NCC(F)(F)F)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.45
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
CA7 P43166 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
PTPN1 P18031 1/20 0.30
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16946101 0.79 EPHX1 (0.47) EPHX1CA2CA1CA7CA13
SCHEMBL17147519 0.79 EPHX1 (0.33) EPHX1CA2CA1
SCHEMBL11173595 0.79 EPHX1 (0.42) EPHX1CA2CA1CA7CA13
SCHEMBL12789664 0.77 EPHX1 (0.60) EPHX1CA2CA1CA7CA13
SCHEMBL1618552 0.75 EPHX1 (0.39) EPHX1CA2CA1CA7CA13
SCHEMBL6305655 0.75 EPHX1 (0.44) EPHX1CA2CA1CA7CA13
SCHEMBL1024523 0.74 CA1 (0.33) CA2CA1CA7CA13
SCHEMBL2835677 0.72 POLB (0.34) EPHX1CA2CA1CA7CA13
SCHEMBL906373 0.72 EPHX1 (0.45) EPHX1CA2CA1CA7CA13
SCHEMBL3371130 0.72 CA1 (0.32) EPHX1CA2CA1CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240253023-A1 PERFLUORINATED AMIDE SALTS AND THEIR USES AS IONIC CONDUCTING MATERIALS MICHOT CHRISTOPHE (FR) 2024-08-01 US disclosed
US-11754926-B2 Method of forming resist pattern, resist composition and method of producing the same TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-12 US disclosed
US-11667731-B2 Stabilized UV active organopalladium compounds as vinyl addition catalysts PROMERUS, LLC (US) 2023-06-06 US disclosed
US-20230127914-A1 RESIST PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-04-27 US disclosed
US-10266503-B1 Sulfoxide ligand metal catalyzed oxidation of olefins THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2019-04-23 US disclosed
US-9929343-B2 Organic semiconductor doping process OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2018-03-27 US disclosed
EP-2325695-B1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORP (JP) 2017-12-20 EP disclosed
US-9818944-B2 Organic semiconductor doping process OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2017-11-14 US disclosed
US-20160240781-A1 ORGANIC SEMICONDUCTOR DOPING PROCESS OXFORD PHOTOVOLTAICS LIMITED (GB) 2016-08-18 US disclosed
US-20160126020-A1 ORGANIC SEMICONDUCTOR DOPING PROCESS OXFORD PHOTOVOLTAICS LIMITED (GB) 2016-05-05 US disclosed
US-20120082936-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2012-04-05 US disclosed
US-20120082936-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2012-04-05 US disclosed
US-20110223537-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND POLYMER JSR CORPORATION (JP) 2011-09-15 US disclosed
US-20110223537-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND POLYMER JSR CORPORATION (JP) 2011-09-15 US disclosed
US-20100099694-A1 2-ANILINO-4-HETEROARYL PYRIMIDINE DERIVATIVES, AND PREPARATION THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS, AND IN PARTICULAR IKK INHIBITORS SANOFI-AVENTIS (FR) 2010-04-22 US disclosed
EP-2108016-A1 2-ANILINO-4-HETEROARYL PYRIMIDINE DERIVATIVES, AND PREPARATION THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS, AND IN PARTICULAR IKK INHIBITORS Sanofi-Aventis (FR) 2009-10-14 EP disclosed
WO-2008099075-A1 2-ANILINO-4-HETEROARYL PYRIMIDINE DERIVATIVES, AND PREPARATION THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS, AND IN PARTICULAR IKK INHIBITORS SANOFI-AVENTIS (FR) 2008-08-21 WO disclosed
EP-0089487-B1 NOVEL N,N'-BIS(TRIFLUOROMETHYLSULFONYL)OXAMIDES AND CHEMILUMINESCENT COMPOSITIONS CONTAINING THE SAME AMERICAN CYANAMID COMPANY (US) 1987-06-16 EP disclosed
US-4407743-A REACTION WITH PEROXIDE IN PRESENCE OF FLUORESCER AMERICAN CYANAMID COMPANY (US) 1983-10-04 US disclosed
EP-0089487-A2 Novel N,N'-bis(trifluoromethylsulfonyl)oxamides and chemiluminescent compositions containing the same AMERICAN CYANAMID COMPANY (US) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099694-A1 2-ANILINO-4-HETEROARYL PYRIMIDINE DERIVATIVES, AND PREPARATION THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS, AND IN PARTICULAR IKK INHIBITORS CHUK, IKBKB, IKBKE EPHX1 3024/4885CA2 4252/4885CA1 4822/4885
US-20240253023-A1 PERFLUORINATED AMIDE SALTS AND THEIR USES AS IONIC CONDUCTING MATERIALS AFF4, AFF2, AFF1 EPHX1 1533/4885CA2 303/4885CA1 627/4885
US-10266503-B1 Sulfoxide ligand metal catalyzed oxidation of olefins YAP1, ICOSLG, SPIN3 EPHX1 2305/4885CA2 3802/4885CA1 3255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.