SCHEMBL3574293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6467427	0.84	SMN1; SMN2 (0.52)	PARP1PARP2PARP3GAAPOLB
	SCHEMBL6505228	0.83	KDM4E (0.55)	PARP1PARP2PARP3GAAIKBKB
	SCHEMBL3568441	0.83	ALDH1A1 (0.54)	PARP1PARP2PARP3GAAPOLB
	SCHEMBL12800605	0.82	RAB9A (0.55)	PARP1GAAIKBKBNOTUMKDM4E
	SCHEMBL3574295	0.80	PARP1 (0.50)	PARP1PARP2PARP3GAAPOLB
	SCHEMBL21071035	0.79	TP53 (0.57)	GAAPOLBALDH1A1HPGDNPC1
	SCHEMBL31664230	0.79	TP53 (0.57)	GAAPOLBALDH1A1HPGDNPC1
	SCHEMBL12800042	0.77	IRAK4 (0.50)	GAAPOLBIKBKBCCNA2CDK2
	SCHEMBL13811464	0.77	PARP1 (0.48)	PARP1PARP2PARP3GAAPOLB
	SCHEMBL27676613	0.76	PARP1 (0.48)	PARP1PARP2PARP3GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.