Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581360 | 0.90 | MCL1 (0.40) | MCL1 | |
| SCHEMBL3582291 | 0.88 | MCL1 (0.39) | MCL1 | |
| SCHEMBL3577275 | 0.88 | MCL1 (0.39) | MCL1 | |
| SCHEMBL3578417 | 0.87 | MCL1 (0.38) | MCL1 | |
| SCHEMBL3586188 | 0.86 | NR3C1 (0.43) | NR3C1 | |
| SCHEMBL3571223 | 0.85 | MAPK14 (0.39) | MCL1 | |
| SCHEMBL3580861 | 0.85 | MCL1 (0.38) | MCL1RCE1 | |
| SCHEMBL3583628 | 0.83 | MCL1 (0.40) | MCL1 | |
| SCHEMBL3576028 | 0.82 | MCL1 (0.39) | MCL1 | |
| SCHEMBL12521053 | 0.81 | TACR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |