Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Bromide SCHEMBL5964841 | 0.88 | — | — | |
| SCHEMBL20389321 | 0.88 | TSHR (1.00) | TSHRALDH1A1TRPA1TDP1CES2 | |
| Benzyl Bromide SCHEMBL5757393 | 0.88 | TSHR (1.00) | TSHRALDH1A1TRPA1TDP1CES2 | |
| Benzyl Bromide SCHEMBL1331189 | 0.88 | — | — | |
| Benzyl Bromide SCHEMBL9000955 | 0.88 | TSHR (1.00) | TSHRALDH1A1TRPA1TDP1CES2 | |
| Benzyl Bromide SCHEMBL1066 | 0.88 | — | — | |
| Benzyl Bromide SCHEMBL8426405 | 0.86 | TSHR (0.74) | TSHRALDH1A1TRPA1TDP1CES2 | |
| Benzyl Bromide SCHEMBL28763610 | 0.86 | ALDH1A1 (0.82) | TSHRALDH1A1TRPA1TDP1CES2 | |
| Benzyl Bromide SCHEMBL905931 | 0.85 | — | — | |
| Benzyl Bromide SCHEMBL4313280 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807827-B2 | Procedure for preparing 11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazineyl)-dibenzo[b,f] [1,4]thiazepine | INKE, S.A. (ES) | 2010-10-05 | — | — | US | disclosed |
| EP-1660468-B1 | PROCEDURE FOR PREPARING 11-(4-[2-(2-HYDROXYETHOXY)ETHYL]-1-PIPERAZINYL)-DIBENZO[B,F][1,4]THIAZEPINE | INKE SA (ES) | 2007-07-18 | — | — | EP | disclosed |
| US-20060189594-A1 | Procedure for preparing a pharmaceutically active compound | INKE, S.A. (ES) | 2006-08-24 | — | — | US | disclosed |
| EP-1660468-A2 | PROCEDURE FOR PREPARING 11-(4-[2-(2-HYDROXYETHOXY)ETHYL]-1-PIPERAZINYL)-DIBENZO[B,F][1,4]THIAZEPINE | INKE, S.A. (ES) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014590-A2 | PROCEDURE FOR PREPARING 11-(4`2-(2-HYDROXYETHOXY )ETHYL!-1-PIPERAZINYL!-DIBENZO`B,F!`1,4!THIAZEPINE | INKE, S.A. (ES) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189594-A1 | Procedure for preparing a pharmaceutically active compound | CYP3A5, CYP2C19, CYP3A7 | TSHR 1776/4885ALDH1A1 876/4885TRPA1 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.