Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889221 | 0.89 | MIF (0.39) | KMT2ATSHRALDH1A1ALOX15ESR1 | |
| SCHEMBL10154525 | 0.74 | KMT2A (0.38) | KMT2AMEN1CYP19A1BCL2SLC6A2 | |
| SCHEMBL8763183 | 0.72 | MIF (0.39) | KMT2ATSHRALDH1A1ALOX15ESR1 | |
| SCHEMBL2241061 | 0.72 | MIF (0.39) | KMT2ATSHRALDH1A1ALOX15ESR1 | |
| SCHEMBL25039218 | 0.72 | KMT2A (0.52) | KMT2AMEN1CYP19A1KIF11BCL2 | |
| SCHEMBL9317593 | 0.72 | ESR1 (0.60) | KMT2AMEN1CYP19A1KIF11BCL2 | |
| SCHEMBL10838797 | 0.72 | CYP19A1 (0.64) | KMT2AMEN1CYP19A1KIF11BCL2 | |
| SCHEMBL25119687 | 0.69 | CYP19A1 (0.37) | KMT2AMEN1CYP19A1KCNH2TSHR | |
| SCHEMBL4062666 | 0.69 | KMT2A (0.82) | KMT2AMEN1CYP19A1KIF11BCL2 | |
| SCHEMBL16144309 | 0.69 | KMT2A (0.82) | KMT2AMEN1CYP19A1KIF11BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713786-B1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-7655600-B2 | 4,5-Dihydro-4-methyloxazol-2-yl)-[2-(3-chloro-phenyl)-1-phenyl-ethyl]-amine; 1-[1-(4-Chlorophenyl)-2-phenyl-ethyl]-(4,5-dihydrothiazol-2-yl)-amine; animal pests; agriculture; broad activity spectrum against difficult to control insects etc. | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-02 | — | — | US | disclosed |
| US-20080161403-A1 | 1-(1,2 Diphenyl-Ethyl)-3-(2-Hydroxyethyl)-Thiourea Compounds For Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | US | disclosed |
| EP-1890541-A2 | 1-(1,2-DIPHENYL-ETHYL)-3-(2-HYDROXYETHYL)-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2006125745-A2 | 1-(1,2-DIPHENYL-ETHYL)-3-(2-HYDROXYETHYL)-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| EP-1713786-A1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005063724-A1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | ANXA1, ANTXR2, ANXA2 | KMT2A 1285/4885MEN1 1710/4885CYP19A1 1404/4885 |
| US-20080161403-A1 | 1-(1,2 Diphenyl-Ethyl)-3-(2-Hydroxyethyl)-Thiourea Compounds For Combating Animal Pests | H1-10, H1-3, H1-0 | KMT2A 2322/4885MEN1 3839/4885CYP19A1 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.