Sugi Predict

Sugi Predict / Compounds / SCHEMBL3575799

SCHEMBL3575799

SCHEMBL3575799

Nc1cc(Cl)c(S(N)(=O)=O)cc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 15/20 0.70
▸ CA2 P00918 15/20 0.70
▸ CA9 Q16790 9/20 0.70
▸ CA12 O43570 8/20 0.70
▸ CA4 P22748 7/20 0.70
▸ CA6 P23280 6/20 0.70
▸ CA5A P35218 6/20 0.70
▸ CA7 P43166 6/20 0.70
▸ CA14 Q9ULX7 6/20 0.70
▸ CA5B Q9Y2D0 6/20 0.70
▸ CA3 P07451 4/20 0.70
▸ CA13 Q8N1Q1 4/20 0.56
▸ CISD1 Q9NZ45 1/20 0.56
▸ ALDH1A1 P00352 3/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ APEX1 P27695 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8025657 0.86 CA1 (0.52) CA1CA2CA9CA12CA4
SCHEMBL11132234 0.85 CA1 (0.79) CA1CA2CA9CA12CA4
SCHEMBL8434850 0.84 CA1 (0.50) CA1CA2CA9CA12CA4
SCHEMBL1806519 0.83 CA1 (0.76) CA1CA2CA9CA12CA4
SCHEMBL310205 0.83 CA1 (1.00) CA1CA2CA9CA12CA4
SCHEMBL29376122 0.83 CA1 (1.00) CA1CA2CA9CA12CA4
Hydrochloric Acid SCHEMBL11139867 0.83 CA1 (0.76) CA1CA2CA9CA12CA4
SCHEMBL30659050 0.83 CA1 (1.00) CA1CA2CA9CA12CA4
SCHEMBL22557603 0.81 CA1 (0.47) CA1CA2CA9CA12CA4
SCHEMBL9647910 0.80 CA1 (0.78) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101137660-B Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives as antidiabetic compounds HOFFMANN LA ROCHE 2011-06-15 — — CN disclosed
US-7645753-B2 Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives HOFFMANN-LA ROCHE INC. (US) 2010-01-12 — — US disclosed
EP-1858901-B1 BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS HOFFMANN LA ROCHE (CH) 2008-11-05 — — EP disclosed
CN-101137660-A Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives as antidiabetic compounds HOFFMANN LA ROCHE (CH) 2008-03-05 — — CN disclosed
EP-1858901-A1 BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS F. Hoffmann-La Roche AG (CH) 2007-11-28 — — EP disclosed
WO-2006094682-A1 BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2006-09-14 — — WO disclosed
US-20060205718-A1 Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives F. HOFFMANN-LA ROCHE AG (CH) 2006-09-14 — — US disclosed
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 — — US disclosed
US-5001227-A Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand CIBA-GEIGY CORPORATION (US) 1991-03-19 — — US disclosed
US-4990598-A Colorfastness CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK 1991-02-05 — — US disclosed
US-4680385-A Metal dye complexes containing an azo or azomethine dye and a colorless ligand with the C═N--N═C group CIBA-GEIGY CORPORATION (US) 1987-07-14 — — US disclosed
US-4678851-A FIBER-RACTIVE CIBA-GEIGY CORPORATION (US) 1987-07-07 — — US disclosed
US-4524123-A POLYETHERSILOXANE COPOLYMERS, HIGH MOLECULAR WEIGHT POLYETHYLEN, AND EMULSIFIER AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1985-06-18 — — US disclosed
EP-0054230-B1 MONOAZO DYESTUFFS AND USE AS IMAGE-FORMING DYESTUFFS IN COLOUR-PHOTOGRAPHIC REGISTRATION MATERIALS Agfa-Gevaert AG (DE) 1985-03-20 — — EP disclosed
US-4461827-A Color photographic recording material containing a non-diffusible dye releaser from which a complexible azo dye is released during development AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1984-07-24 — — US disclosed
US-4396710-A Photographic recording material with metal complexable, heterocyclic azo dye AFGA-GEVAERT AKTIENGESELLSCHAFT (DE) 1983-08-02 — — US disclosed
EP-0054230-A2 Monoazo dyestuffs and use as image-forming dyestuffs in colour-photographic registration materials Agfa-Gevaert AG (DE) 1982-06-23 — — EP disclosed
US-4263197-A AMINE SALTS OF CHROMIUM COMPLEXES OF MONOAZO DYES CIBA-GEIGY CORPORATION (US) 1981-04-21 — — US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 — — US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205718-A1 Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives SSTR5, SSTR1, SSTR2 CA1 2974/4885CA2 1232/4885CA9 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.