SCHEMBL8025657

SCHEMBL8025657

Nc1cc(Cl)c(S(=O)(=O)O)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.52
CA2 P00918 6/20 0.52
CA12 O43570 5/20 0.52
CA9 Q16790 5/20 0.52
CA4 P22748 4/20 0.52
CA6 P23280 4/20 0.52
CA5A P35218 4/20 0.52
CA7 P43166 4/20 0.52
CA14 Q9ULX7 4/20 0.52
CA5B Q9Y2D0 4/20 0.52
CA3 P07451 3/20 0.52
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 4/20 0.46
GAA P10253 2/20 0.42
MAPT P10636 1/20 0.42
CA13 Q8N1Q1 2/20 0.42
CISD1 Q9NZ45 1/20 0.42
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651614 0.92 CA1 (0.47) CA1CA2CA12CA9CA4
SCHEMBL3575799 0.86 CA1 (0.70) CA1CA2CA12CA9CA4
SCHEMBL9327065 0.83 CA1 (0.61) CA1CA2CA12CA9CA4
SCHEMBL29516458 0.83 GAA (0.52) CA1CA2CA12CA9CA4
SCHEMBL1708535 0.83 GAA (0.52) CA1CA2CA12CA9CA4
SCHEMBL9787926 0.83 ALDH1A1 (0.55) CA1CA2CA12CA9CA4
SCHEMBL8434850 0.82 CA1 (0.50) CA1CA2CA12CA9CA4
SCHEMBL27903562 0.82 CA1 (0.78) CA1CA2CA12CA9CA4
SCHEMBL11284960 0.82 GAA (0.50) CA1CA2CA12CA9CA4
SCHEMBL11284975 0.82 GAA (0.50) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
CN-1235992-A Water-soluble fiber-reactive dyes, processes for their preparation and their use HOECHST AG (DE) 1999-11-24 CN disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
US-5731421-A COLORFASTNESS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-24 US disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 EP disclosed
EP-0076782-A2 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1983-04-13 EP disclosed
EP-0074928-A2 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
EP-0059355-A2 Use of reactive dyestuffs in dyeing and printing of hydroxylgroups containing fibrous materials BAYER AG (DE) 1982-09-08 EP disclosed
EP-0054230-A2 Monoazo dyestuffs and use as image-forming dyestuffs in colour-photographic registration materials Agfa-Gevaert AG (DE) 1982-06-23 EP disclosed
US-4270918-A METALLIZED TRIAZINE-FUNCTIONAL MONOAZO DYE CIBA-GEIGY CORPORATION (US) 1981-06-02 US disclosed
EP-0024668-A2 Reactive dyestuffs and their use in dyeing and printing hydroxyl groups and nitrogen containing materials BAYER AG (DE) 1981-03-11 EP disclosed
US-4206306-A Reactive phthalocyanine dyestuffs containing a fluorotriazinyl group attached via a nitrogen bridge to the dyestuff molecule BAYER AKTIENGESELLSCHAFT (DE) 1980-06-03 US disclosed
US-4115378-A TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed
US-4052386-A REACTIVE PHTHALOCYANINE DYESTUFFS CONTAINING A FLUOROPYRIMIDINYL GROUP BAYER AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-4007164-A FIBER-REACTIVE, CELLULOSE, WOOL BAYER AKTIENGESELLSCHAFT (DT) 1977-02-08 US disclosed