Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599882 | 0.82 | PPARD (0.52) | PPARDPPARAPPARGHSD17B3SMN1; SMN2 | |
| SCHEMBL5717743 | 0.80 | PPARD (0.47) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL16196902 | 0.79 | PPARD (0.48) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL27233458 | 0.79 | PPARD (0.42) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL13499422 | 0.78 | CYP2C19 (0.52) | CYP2C19POLBCYP2C9ALDH1A1MAPT | |
| SCHEMBL27682431 | 0.77 | PPARD (0.48) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL26499325 | 0.76 | PPARD (0.46) | PPARDPPARAPPARGPOLBHSD17B3 | |
| SCHEMBL21434866 | 0.76 | PPARD (0.42) | PPARDPPARAPPARGHSD17B3 | |
| SCHEMBL21434868 | 0.76 | PPARD (0.42) | PPARDPPARAPPARGHSD17B3 | |
| SCHEMBL21434877 | 0.76 | PPARD (0.42) | PPARDPPARAPPARGHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029620-A1 | SUBSTITUTED TRIAZOLINE, TETRAZOLONE AND IMIDAZOLONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA N.V. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029620-A1 | SUBSTITUTED TRIAZOLINE, TETRAZOLONE AND IMIDAZOLONE DERIVATIVES FOR USE AS A MEDICINE | ADRA2C, ADRB2, CHRNA5 | CYP2C19 185/4885PPARD 697/4885PPARA 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.