SCHEMBL357604

SCHEMBL357604

CC(C)COC(=O)C(C)(C)CCCCl

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
TSHR P16473 4/20 0.36
PRKCA P17252 1/20 0.36
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ACLY P53396 1/20 0.31
MMP8 P22894 1/20 0.30
ACACB O00763 1/20 0.30
ACACA Q13085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23586586 0.95 CYP4F2 (0.45) CYP4F2CYP4A11TSHRPRKCAALDH1A1
SCHEMBL21757419 0.89 TSHR (0.38) CYP4F2CYP4A11TSHRPRKCAALDH1A1
SCHEMBL1908743 0.84 CYP4F2 (0.43) CYP4F2CYP4A11TSHRPRKCAALDH1A1
SCHEMBL1911530 0.84 CYP4F2 (0.47) CYP4F2CYP4A11TSHRPRKCAALDH1A1
SCHEMBL20875724 0.82 CYP4F2 (0.42) CYP4F2CYP4A11TSHRPRKCAALDH1A1
SCHEMBL1911430 0.82 CYP4F2 (0.50) CYP4F2CYP4A11TSHRPRKCAL3MBTL1
SCHEMBL21757361 0.81 TSHR (0.33) TSHRPRKCAALDH1A1TDP1L3MBTL1
SCHEMBL9483233 0.81 CYP4F2 (0.47) CYP4F2CYP4A11TSHRTDP1ACLY
SCHEMBL20747669 0.81 CYP4F2 (0.53) CYP4F2CYP4A11TSHRALDH1A1L3MBTL1
SCHEMBL10087754 0.81 CYP4F2 (0.53) CYP4F2CYP4A11TSHRALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552069-A Improved preparation method of gemfibrozil 山东精进药业有限公司 2025-03-04 CN claimed
CN-113105377-B Preparation method of plasticizer and application of plasticizer in plastic product 新疆欣业恒达塑业有限公司 2022-09-02 CN claimed
CN-113105377-A Preparation method of plasticizer and application of plasticizer in plastic product 程伟 2021-07-13 CN claimed
CN-112592275-A Preparation method of isobutyl 5-chloro-2, 2-dimethylpentanoate 杭州宇龙化工有限公司 2021-04-02 CN claimed
CN-1012896-B 5-(2, the 5-dimethyl phenoxy)-2,2-dimethyl valeric acid preparation method's improvement WARNER LAMBERT CO (US) 1991-06-19 CN claimed
EP-0226161-B1 IMPROVED PROCESS FOR PREPARING 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID WARNER-LAMBERT COMPANY (US) 1989-11-08 EP claimed
CN-86108472-A 5-(2, the 5-dimethyl phenoxy)-2,2-dimethyl valeric acid preparation method's improvement 1987-07-22 CN claimed
EP-0226161-A1 Improved process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid WARNER-LAMBERT COMPANY (US) 1987-06-24 EP claimed
US-4665226-A Process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid WARNER-LAMBERT COMPANY (US) 1987-05-12 US claimed
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 EP disclosed
CN-121342645-A Preparation method of gemfibrozil Ji Zazhi A key intermediate 山东精进药业有限公司 2026-01-16 CN disclosed
CN-121248394-A Synthesis method of gemfibrozil Ji Zazhi A 山东精进药业有限公司 2026-01-02 CN disclosed
US-20250313522-A1 PHENOXY CARBOXYLIC ACID COMPOUNDS AND MEDICAL USES THEREOF QINGDAO RISING BIOTECHNOLOGY CO., LTD (CN) 2025-10-09 US disclosed
US-12365643-B2 Phenoxy carboxylic acid compounds and medical uses thereof QINGDAO RISING BIOTECHNOLOGY CO., LTD (CN) 2025-07-22 US disclosed
CN-101613334-A Flavone derivative and medicinal use thereof INST PHARM & TOXICOLOGY AMMS 2009-12-30 CN disclosed
CN-1012896-B 5-(2, the 5-dimethyl phenoxy)-2,2-dimethyl valeric acid preparation method's improvement WARNER LAMBERT CO (US) 1991-06-19 CN disclosed
EP-0226161-B1 IMPROVED PROCESS FOR PREPARING 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID WARNER-LAMBERT COMPANY (US) 1989-11-08 EP disclosed
CN-86108472-A 5-(2, the 5-dimethyl phenoxy)-2,2-dimethyl valeric acid preparation method's improvement 1987-07-22 CN disclosed
EP-0226161-A1 Improved process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid WARNER-LAMBERT COMPANY (US) 1987-06-24 EP disclosed
US-4665226-A Process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid WARNER-LAMBERT COMPANY (US) 1987-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365643-B2 Phenoxy carboxylic acid compounds and medical uses thereof PYGL, SLC10A1, GYS2 CYP4F2 116/4885CYP4A11 6/4885TSHR 2525/4885
US-20250313522-A1 PHENOXY CARBOXYLIC ACID COMPOUNDS AND MEDICAL USES THEREOF PYGL, SLC10A1, GYS2 CYP4F2 116/4885CYP4A11 6/4885TSHR 2525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.