Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277789 | 0.82 | CA1 (0.56) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL5175288 | 0.81 | ALDH1A1 (0.66) | — | |
| Hydrochloric Acid SCHEMBL3950177 | 0.81 | CA1 (0.54) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3942498 | 0.80 | MEN1 (0.71) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3939260 | 0.80 | MEN1 (0.56) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3947875 | 0.79 | MEN1 (0.51) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3276784 | 0.79 | MEN1 (0.54) | MEN1CYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL3944192 | 0.78 | MEN1 (0.50) | MEN1CYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL4158004 | 0.78 | MEN1 (0.53) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3272732 | 0.77 | P2RX7 (0.57) | MEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |