SCHEMBL3576498

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3587979	0.91	PDK2 (0.38)	RXRANR1H2NR1H3PTGS2ALDH1A1
	SCHEMBL3473684	0.82	RXRA (0.56)	RXRANR1H2NR1H3PTGS2SLC22A12
	SCHEMBL15459634	0.79	HPGD (0.39)	RXRANR1H2NR1H3STIM1ORAI1
	SCHEMBL3473241	0.73	RXRA (0.54)	RXRANR1H2NR1H3PTGS2KDM4E
	SCHEMBL3577069	0.73	PTGS2 (0.41)	RXRANR1H2NR1H3PTGS2KDM4E
	SCHEMBL3586753	0.73	NR1H2 (0.66)	RXRANR1H2NR1H3PTGS2PTGS1
	SCHEMBL3582716	0.72	RXRA (0.42)	RXRANR1H2NR1H3PTGS2PTGS1
	SCHEMBL14621333	0.72	RXRA (0.45)	RXRANR1H2NR1H3PTGS2PTGS1
	SCHEMBL3582884	0.71	RXRA (0.38)	RXRANR1H2NR1H3PTGS2MEN1
	SCHEMBL3576651	0.71	RXRA (0.47)	RXRANR1H2NR1H3PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.