Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891483 | 0.87 | AVPR2 (0.51) | AVPR2AVPR1AROCK2MEN1RAB9A | |
| SCHEMBL3576454 | 0.87 | AVPR2 (0.49) | AVPR2AVPR1AROCK2MAPT | |
| SCHEMBL5890729 | 0.85 | AVPR2 (0.50) | AVPR2AVPR1ANAMPT | |
| SCHEMBL3580102 | 0.83 | AVPR2 (0.50) | AVPR2AVPR1ANAMPT | |
| SCHEMBL3553453 | 0.83 | AVPR2 (0.48) | AVPR2AVPR1AROCK2ALDH1A1GAA | |
| SCHEMBL3552894 | 0.83 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL3575226 | 0.82 | ROCK2 (0.39) | AVPR2AVPR1AROCK2NAMPT | |
| SCHEMBL5891185 | 0.81 | AVPR2 (0.50) | AVPR2AVPR1AALDH1A1RAB9ANAMPT | |
| SCHEMBL5891188 | 0.81 | AVPR2 (0.51) | AVPR2AVPR1AROCK2ALDH1A1MEN1 | |
| SCHEMBL5784283 | 0.80 | AVPR2 (0.55) | AVPR2AVPR1ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687623-B2 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH LLC (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687623-B2 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH LLC (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687623-B2 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH LLC (US) | 2010-03-30 | — | — | US | disclosed |
| US-20060258645-A1 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH (US) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258645-A1 | Pyrrolobenzodiazepines and heterocyclic carboxamide derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | FSHR, GNRHR, PRLHR | AVPR2 9/4885AVPR1A 16/4885ROCK2 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.