Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 8/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3553453 | 0.89 | AVPR2 (0.48) | AVPR2AVPR1ATP53LMNAPOLB | |
| SCHEMBL5890729 | 0.88 | AVPR2 (0.50) | AVPR2AVPR1ATP53LMNAPOLB | |
| SCHEMBL5891483 | 0.83 | AVPR2 (0.51) | AVPR2AVPR1ALMNAPOLB | |
| SCHEMBL3576884 | 0.83 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL5891209 | 0.83 | ALDH1A1 (0.48) | AVPR2TP53POLB | |
| SCHEMBL3580102 | 0.82 | AVPR2 (0.50) | AVPR2AVPR1A | |
| SCHEMBL3560078 | 0.82 | LMNA (0.44) | AVPR2AVPR1ATP53LMNA | |
| SCHEMBL5891358 | 0.81 | AVPR2 (0.49) | AVPR2AVPR1ATP53LMNAPOLB | |
| SCHEMBL3576454 | 0.81 | AVPR2 (0.49) | AVPR2AVPR1A | |
| SCHEMBL6651468 | 0.81 | AVPR2 (0.54) | AVPR2AVPR1AKCNH2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287522-A1 | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists | WYETH (US) | 2006-12-21 | — | — | US | claimed |
| US-7678787-B2 | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists | WYETH (US) | 2010-03-16 | — | — | US | disclosed |
| US-20060287522-A1 | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists | WYETH (US) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287522-A1 | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists | FSHR, GNRHR, PRLHR | AVPR2 26/4885AVPR1A 51/4885KCNH2 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.