Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316131 | 0.87 | PPARG (1.00) | PPARG | |
| SCHEMBL3572505 | 0.84 | PPARG (1.00) | PPARG | |
| SCHEMBL4656115 | 0.84 | PPARG (0.57) | PPARGKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL4655615 | 0.81 | PPARG (0.92) | PPARG | |
| SCHEMBL3572575 | 0.80 | PPARG (1.00) | PPARGKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL4658647 | 0.80 | PPARG (0.91) | PPARGMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL13316147 | 0.78 | PPARG (1.00) | PPARG | |
| SCHEMBL4657598 | 0.78 | PPARG (0.86) | PPARG | |
| SCHEMBL4657596 | 0.78 | PPARG (0.86) | PPARG | |
| SCHEMBL3569618 | 0.77 | PPARG (0.59) | PPARGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745439-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-29 | — | — | US | disclosed |
| EP-1756036-A4 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-04-16 | — | — | EP | disclosed |
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | JEIL PHARM. CO., LTD. (KR) | 2007-09-27 | — | — | US | disclosed |
| EP-1756036-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100297-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | INSR, GPR119, PPARA | PPARG 8/4885KDM4E 3150/4885MEN1 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.