SCHEMBL3579715

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13462397	0.82	JAK2 (0.40)	KMT2AMEN1MAPTRAB9AHTT
	SCHEMBL1753018	0.81	MEN1 (0.51)	KMT2AMEN1MAPTRAB9AHTT
	SCHEMBL3587122	0.79	KMT2A (0.49)	KMT2AMEN1MAPTRAB9AHTT
	SCHEMBL2726739	0.79	HTT (0.65)	KMT2AMEN1MAPTRAB9AHTT
	SCHEMBL642257	0.74	CES2 (0.46)	KMT2AMEN1RAB9AHTTLMNA
	SCHEMBL7605886	0.73	KMT2A (0.59)	KMT2AMEN1MAPTRAB9AHTT
	SCHEMBL18377680	0.72	CES2 (0.44)	KMT2AMEN1RAB9AHTTLMNA
	SCHEMBL6860892	0.72	GAA (0.61)	KMT2AMEN1MAPTRAB9AHTT
	SCHEMBL6127974	0.72	JAK2 (0.69)	MAPTRAB9ANPC1SMN1; SMN2MAOB
	SCHEMBL15205641	0.72	MEN1 (0.55)	KMT2AMEN1MAPTRAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.