Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 13/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806890 | 0.84 | GAA (0.62) | GAAMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL2726739 | 0.83 | HTT (0.65) | GAASMN1; SMN2MAPTALDH1A1TDP1 | |
| SCHEMBL8372493 | 0.78 | CES2 (0.61) | GAAKDM4EKMT2ALMNANPC1 | |
| SCHEMBL7605886 | 0.78 | KMT2A (0.59) | GAASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL15597703 | 0.76 | GAA (0.69) | GAAMAPTALDH1A1GFERTDP1 | |
| SCHEMBL15597845 | 0.76 | GAA (0.69) | GAAMAPTALDH1A1KDM4EGFER | |
| SCHEMBL10474111 | 0.75 | GAA (0.53) | GAASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL27876858 | 0.74 | CES2 (0.52) | SMN1; SMN2MAPTKDM4EKMT2APOLB | |
| SCHEMBL15597972 | 0.74 | GAA (0.57) | GAASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL8084094 | 0.74 | GAA (0.51) | GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797574-B1 | 1,3,4-OXADIAZINE DERIVATIVES HAVING A PESTICIDE EFFECT | BAYER CROPSCIENCE AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6013804-A | FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-11 | — | — | US | disclosed |
| US-5883091-A | 1,3,4-oxadiazine derivatives having a pesticide effect | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0797574-A1 | 1,3,4-OXADIAZINE DERIVATIVES HAVING A PESTICIDE EFFECT | BAYER AG (DE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018624-A1 | 1,3,4-OXADIAZINE DERIVATIVES HAVING A PESTICIDE EFFECT | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-20 | — | — | WO | disclosed |