SCHEMBL3579822

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3576860	0.93	DRD2 (0.70)	KCNA5DRD3DRD2HTR2AHRH3
	SCHEMBL13438263	0.91	HRH3 (0.67)	KCNA5DRD3DRD2HTR2AHRH3
	Hydrochloric Acid SCHEMBL5935361	0.89	HRH3 (0.67)	DRD3DRD2HTR2AHRH3HRH1
	SCHEMBL3581124	0.86	HRH3 (0.67)	DRD2HTR2AHRH3HRH1KCNH2
	SCHEMBL13437994	0.85	HRH3 (0.60)	DRD2HTR2AHRH3HRH1KCNH2
	SCHEMBL3576908	0.83	HRH3 (0.72)	KCNA5DRD3DRD2HTR2AHRH3
	SCHEMBL3584184	0.83	LMNA (0.63)	KCNA5DRD3DRD2HTR2AMEN1
	SCHEMBL7804413	0.83	MAPT (0.60)	KCNA5DRD3DRD2HTR2AMEN1
	SCHEMBL16150148	0.83	DRD2 (0.62)	KCNA5DRD3DRD2HTR2AHRH1
	SCHEMBL3582147	0.83	LMNA (0.59)	KCNA5DRD3DRD2HTR2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.