⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333001 | 0.98 | — | — | |
| SCHEMBL397518 | 0.95 | CES2 (0.32) | — | |
| SCHEMBL393192 | 0.93 | CES2 (0.34) | — | |
| SCHEMBL395575 | 0.93 | CES2 (0.34) | — | |
| SCHEMBL11075197 | 0.92 | — | — | |
| SCHEMBL10537148 | 0.92 | — | — | |
| SCHEMBL16486227 | 0.91 | — | — | |
| SCHEMBL396765 | 0.89 | — | — | |
| SCHEMBL5702084 | 0.89 | — | — | |
| SCHEMBL9576543 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523338-B9 | TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE (US) | 2023-10-18 | — | — | EP | claimed |
| EP-3523338-B1 | TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE (US) | 2023-07-12 | — | — | EP | claimed |
| EP-4011940-A1 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | Johnson & Johnson Vision Care, Inc. (US) | 2022-06-15 | — | — | EP | claimed |
| US-11360241-B2 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2022-06-14 | — | — | US | claimed |
| EP-3406642-B1 | WATER-SOLUBLE SILICONE MACROMER, SILICONE HYDROGEL COMPOSITION, SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MANUFACTURING THE SAME | PEGAVISION CORP (TW) | 2021-07-21 | — | — | EP | claimed |
| US-20210149084-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2021-05-20 | — | — | US | claimed |
| US-10975040-B2 | Hydroxyphenyl naphthotriazoles as polymerizable blockers of high energy light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-04-13 | — | — | US | claimed |
| US-10935696-B2 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-03-02 | — | — | US | claimed |
| EP-2794727-B2 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE (US) | 2020-10-28 | — | — | EP | claimed |
| EP-1588829-B1 | Method for preparing a mold part useful for transfering a coating onto an optical substrate | ESSILOR INT (FR) | 2020-08-26 | — | — | EP | claimed |
| WO-1992007013-A1 | NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM | PERMEABLE TECHNOLOGIES, INC. (US) | 1992-04-30 | — | — | WO | claimed |
| US-5084537-A | Contact lenses from organosilicon monomers that are oxygen permeable | BAUSCH & LOMB, INCORPORATED (US) | 1992-01-28 | — | — | US | claimed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | claimed |
| WO-1991015527-A1 | NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE CONTACT LENSES | PERMEABLE CONTACT LENSES, INC. (US) | 1991-10-17 | — | — | WO | claimed |
| EP-0452098-A2 | Silicone-containing block copolymers and macromonomers | E.I. du Pont de Nemours and Company (US) | 1991-10-16 | — | — | EP | claimed |
| US-5057578-A | Contact lenses | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | claimed |
| US-5002979-A | Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent | BAUSCH & LOMB INCORPORATED (US) | 1991-03-26 | — | — | US | claimed |
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | claimed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | claimed |
| US-4661573-A | INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE | PARAGON OPTICAL INC. (US) | 1987-04-28 | — | — | US | claimed |