SCHEMBL396765

SCHEMBL396765

C=C(C)COCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35806 0.89
SCHEMBL333001 0.87
SCHEMBL397518 0.87 CES2 (0.32)
SCHEMBL393192 0.85 CES2 (0.34)
SCHEMBL395575 0.85 CES2 (0.34)
SCHEMBL9303992 0.84
SCHEMBL9302987 0.84
SCHEMBL9715003 0.82
SCHEMBL9715002 0.82
SCHEMBL10537148 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11427666-B2 Silicone-containing acrylic polymers for transdermal drug delivery compositions NOVEN PHARMACEUTICALS, INC. (US) 2022-08-30 US disclosed
US-20200277424-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2020-09-03 US disclosed
EP-3179989-B1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMA (US) 2019-06-12 EP disclosed
EP-3179989-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS Noven Pharmaceuticals, INC. (US) 2017-06-21 EP disclosed
WO-2016018858-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 WO disclosed
US-20160030362-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 US disclosed
US-8110697-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-02-07 US disclosed
US-8101789-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-01-24 US disclosed
EP-2125833-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
EP-2125834-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
US-20100041909-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-18 US disclosed
US-20100029972-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-04 US disclosed
EP-0611783-B1 Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives CIBA GEIGY AG (CH) 1998-04-01 EP disclosed
US-5376378-A Transdermal drug delivery CIBA-GEIGY CORP. (US) 1994-12-27 US disclosed
EP-0611783-A1 Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives CIBA-GEIGY AG (CH) 1994-08-24 EP disclosed
US-5288827-A Drug selivery CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed