Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.81 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.58 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655615 | 0.94 | PPARG (0.92) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL3572505 | 0.89 | PPARG (1.00) | PPARG | |
| SCHEMBL3577919 | 0.89 | PPARG (0.77) | PPARGFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL13316049 | 0.85 | PPARG (0.82) | PPARG | |
| SCHEMBL4658647 | 0.85 | PPARG (0.91) | PPARG | |
| SCHEMBL4657596 | 0.83 | PPARG (0.86) | PPARG | |
| SCHEMBL4657598 | 0.83 | PPARG (0.86) | PPARG | |
| SCHEMBL3577620 | 0.80 | PPARG (0.62) | PPARGMAOAMAOB | |
| SCHEMBL3567958 | 0.79 | PPARG (0.63) | PPARGMAOAMAOB | |
| Cyclohexylamine SCHEMBL3577623 | 0.79 | PPARG (0.63) | PPARGFGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745439-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-29 | — | — | US | disclosed |
| US-7741323-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-22 | — | — | US | disclosed |
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | JEIL PHARM. CO., LTD. (KR) | 2007-09-27 | — | — | US | disclosed |
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-08-09 | — | — | US | disclosed |
| EP-1740531-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100303-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | INSR, PPARD, GPR119 | PPARG 5/4885FGFR1 134/4885FGFR2 236/4885 |
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | INSR, GPR119, PPARA | PPARG 8/4885FGFR1 41/4885FGFR2 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.