Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579342 | 0.89 | GPR119 (0.54) | GPR119DPP4STSKDM4EPKM | |
| SCHEMBL22559199 | 0.89 | GPR119 (0.45) | GPR119DPP4STSYAP1JAK2 | |
| SCHEMBL20615628 | 0.88 | GPR119 (0.53) | GPR119DPP4STSKDM4EPKM | |
| SCHEMBL28347845 | 0.88 | GPR119 (0.53) | GPR119DPP4STSKDM4EPKM | |
| SCHEMBL962609 | 0.83 | GPR119 (0.55) | GPR119STSKDM4EPKMYAP1 | |
| SCHEMBL962607 | 0.83 | GPR119 (0.55) | GPR119STSKDM4EPKMYAP1 | |
| SCHEMBL19674445 | 0.81 | KDM4E (0.53) | GPR119STSKDM4EPKMYAP1 | |
| SCHEMBL14406041 | 0.81 | KDM4E (0.53) | GPR119STSKDM4EPKMYAP1 | |
| SCHEMBL22284215 | 0.81 | GPR119 (0.54) | GPR119STSKDM4EPKMYAP1 | |
| SCHEMBL9910680 | 0.81 | PRMT5 (0.61) | GPR119STSKDM4EPKMYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | Wurster, Siegfried (FI) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | SSTR1, SSTR4, SSTR3 | GPR119 21/4885DPP4 117/4885STS 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.