SCHEMBL3579342

SCHEMBL3579342

CC(C)(C)OC(=O)N1CCC(C(N)CCOCc2ccccc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 4/20 0.54
DPP4 P27487 1/20 0.52
STS P08842 1/20 0.49
JAK2 O60674 1/20 0.47
JAK1 P23458 1/20 0.47
KDM4E B2RXH2 1/20 0.47
PKM P14618 1/20 0.47
YAP1 P46937 3/20 0.47
SMN1; SMN2 Q16637 4/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
GAA P10253 1/20 0.45
THRB P10828 1/20 0.45
CYP2C19 P33261 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 1/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20615628 0.95 GPR119 (0.53) GPR119DPP4STSJAK2JAK1
SCHEMBL28347845 0.95 GPR119 (0.53) GPR119DPP4STSJAK2JAK1
SCHEMBL3580922 0.89 GPR119 (0.56) GPR119DPP4STSJAK2JAK1
SCHEMBL22284215 0.85 GPR119 (0.54) GPR119STSJAK2JAK1KDM4E
SCHEMBL3583084 0.85 DPP4 (0.53) GPR119DPP4STSKDM4EPKM
SCHEMBL22284216 0.84 GPR119 (0.53) GPR119DPP4STSJAK2JAK1
SCHEMBL3251863 0.82 KDM4E (0.58) GPR119STSJAK2JAK1KDM4E
SCHEMBL22559199 0.80 GPR119 (0.45) GPR119DPP4STSJAK2JAK1
SCHEMBL21458596 0.80 STS (0.53) GPR119STSJAK2JAK1KDM4E
SCHEMBL27271703 0.80 KDM4E (0.56) GPR119STSJAK2JAK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 GPR119 21/4885DPP4 117/4885STS 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.