Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584408 | 0.88 | MEN1 (0.39) | STAT3CNR1UBE2MDCUN1D1 | |
| SCHEMBL3576581 | 0.88 | SCN9A (0.39) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL3581040 | 0.87 | STAT3 (0.39) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL3571214 | 0.86 | CNR1 (0.38) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL27750943 | 0.83 | CNR1 (0.40) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL3574302 | 0.82 | CNR1 (0.42) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL3575613 | 0.82 | SCN9A (0.39) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL27750956 | 0.82 | STAT3 (0.38) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL3581035 | 0.81 | CNR1 (0.39) | STAT3CNR1SCN9ASLC6A9KCNH2 | |
| SCHEMBL3580280 | 0.80 | DCUN1D1 (0.36) | STAT3CNR1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |