Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581431 | 1.00 | ADRB3 (0.62) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL3581428 | 1.00 | ADRB3 (0.62) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1352658 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1352656 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1352451 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1351570 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1352449 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1351574 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1352446 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1LMNAADRB2HIF1A | |
| SCHEMBL1352631 | 0.86 | ADRB3 (0.54) | ADRB3ADRB1LMNAADRB2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759540-A2 | Beta-3 receptor ligands and their use in therapy | Universita' Degli Studi di Bari (IT) | 2014-07-30 | — | — | EP | disclosed |
| US-8354412-B2 | Beta-3 receptor ligands and their use in therapy | UNIVERSITA' DEGLI STUDI DI BARI (IT) | 2013-01-15 | — | — | US | disclosed |
| US-20100075977-A1 | BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY | UNVERSITA' DEGLI STUDI DI BARI (IT) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075977-A1 | BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY | ADRB3, ADRB2, ADRB1 | ADRB3 1/4885ADRB1 3/4885LMNA 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.